anti-Human FAS antibody for Fluorescence Microscopy

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • ALPS1A
  • APO-1
  • APT1
  • CD95
  • FAS1
  • FASTM
  • TNFRSF6
  • AI196731
  • APO1
  • TNFR6
  • Tnfrsf6
  • lpr
  • Fas cell surface death receptor
  • Fas (TNF receptor superfamily member 6)
  • FAS
  • Fas
  • fas
Reactivity
Human
636
113
99
13
11
10
6
6
3
3
3
3
2
1
Host
Mouse
406
300
24
5
4
3
3
Clonality
Monoclonal
Conjugate
This FAS antibody is un-conjugated
73
63
49
30
15
8
7
6
5
5
5
4
4
4
4
4
4
2
2
2
2
2
2
1
1
1
1
1
1
Application
Fluorescence Microscopy (FM), Functional Studies (Func), Flow Cytometry (FACS)
331
320
210
146
105
82
61
54
52
46
23
19
12
7
6
6
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
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Catalog No. ABIN2689464
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General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Reactivity Human
(636), (113), (99), (13), (11), (10), (6), (6), (3), (3), (3), (3), (2), (1)
Host Mouse
(406), (300), (24), (5), (4), (3), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FAS antibody is un-conjugated
(73), (63), (49), (30), (15), (8), (7), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Fluorescence Microscopy (FM), Functional Studies (Func), Flow Cytometry (FACS)
(331), (320), (210), (146), (105), (82), (61), (54), (52), (46), (23), (19), (12), (7), (6), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-FAS Antibody

Target Details FAS Application Details Handling References for anti-FAS antibody (ABIN2689464) Images
Brand BD Pharmingen™
Characteristics Reacts with a 45 kD type I membrane molecule also known as APO-1, or Fas antigen. CD95 belongs to the tumor necrosis factor receptor (TNF-R) family of proteins and is expressed on various cells, including activated T cells and B cells. The interaction of CD95, Fas antigen, with Fas ligand is one of the many mechanisms that lead to apoptosis or programmed cell death. The interaction of CD95 expressing target cells with Fas ligand on cytotoxic T cells induces an apoptotic signal leading to target cell death. It has been reported that apoptosis is the mechanism used by the immune system in clonal deletion of self-reactive T cells during embryological development. Jurkat cells treated for 6 hours with CD95 (EOS9.1) Jurkat cells treated for 6 hours with mouse IgM isotype control

BD Pharmingen™ Purified Mouse Anti-Human CD95 - Purified - Clone EOS9.1 - Isotype Mouse IgM, κ - Reactivity Hu - 0.1 mg
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Clone EOS9-1
Isotype IgM, kappa

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling References for anti-FAS antibody (ABIN2689464) Images back to top
Antigen
Alternative Name CD95 (FAS Antibody Abstract)
Background Synonyms: Fas/APO-1
Pathways p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling References for anti-FAS antibody (ABIN2689464) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details References for anti-FAS antibody (ABIN2689464) Images back to top
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing no preservative.
Preservative Without preservative
Handling Advice This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Storage 4 °C
Storage Comment Store undiluted at 4°C.

References for anti-FAS antibody (ABIN2689464)

Product Details anti-FAS Antibody Target Details FAS Application Details Handling Images back to top
Product cited in:

Krammer, Dhein, Walczak, Behrmann, Mariani, Matiba, Fath, Daniel, Knipping, Westendorp: "The role of APO-1-mediated apoptosis in the immune system." in: Immunological reviews, Vol. 142, pp. 175-91, 1995

Nagata, Golstein: "The Fas death factor." in: Science (New York, N.Y.), Vol. 267, Issue 5203, pp. 1449-56, 1995

Rouvier, Luciani, Golstein: "Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity." in: The Journal of experimental medicine, Vol. 177, Issue 1, pp. 195-200, 1993