anti-Human FAS antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • ALPS1A
  • APO-1
  • APT1
  • CD95
  • FAS1
  • FASTM
  • TNFRSF6
  • FASL
  • TNFSF6
  • AI196731
  • APO1
  • TNFR6
  • Tnfrsf6
  • lpr
  • Fas cell surface death receptor
  • Fas ligand
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  • Fas (TNF receptor superfamily member 6)
  • FAS
  • FASLG
  • YWHAZ
  • Fas
  • fas
Epitope
AA 26-173
49
25
18
15
15
15
13
12
12
11
11
9
9
8
8
7
7
6
5
5
5
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
743
117
97
22
11
7
5
4
3
3
3
2
1
Host
Rabbit
494
318
24
5
4
3
3
Clonality
Polyclonal
Conjugate
This FAS antibody is un-conjugated
74
62
51
33
19
12
11
9
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
400
359
212
204
103
93
87
83
52
41
22
20
11
8
8
7
7
4
3
3
3
2
2
2
2
2
1
1
1
1
1
Options
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Catalog No. ABIN3042387
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
22.285042 ABIN94249 FACS IHC (p) FITC Mouse IgG1 Log in to see LT95 5
19.285042 ABIN192280 FACS IHC (p) PE Mouse IgG1 Log in to see LT95 5
17.5 ABIN1106610 IHC (fro) IF IHC (p) Mouse IgG1 Log in to see UB2 16
16 ABIN3030904 IHC (p) WB Rabbit IgG AA 26-173 Log in to see Polyclonal 0
14.785042 ABIN94248 FACS IHC (p) Mouse IgG1 Log in to see LT95 5
14.785042 ABIN1302576 FACS IHC (p) APC Mouse IgG1 Log in to see LT95 4
11.814635 ABIN351542 FACS IHC IHC (p) Mouse IgG1 Log in to see LT95 0
11.785042 ABIN1020119 IHC (f) IHC (p) Rabbit IgG C-Term Log in to see Polyclonal 0
11.785042 ABIN1020120 IHC (f) IHC (p) Rabbit IgG C-Term Log in to see Polyclonal 0
11.502789 ABIN266061 IHC (p) IHC WB Rabbit Log in to see Polyclonal 4
11.502789 ABIN4310551 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
10 ABIN574330 ELISA IHC IHC (p) WB Goat AA 224-237 Log in to see Polyclonal 0
10 ABIN5577915 IF IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
8.5 ABIN1387305 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
7.0027885 ABIN5948254 FACS ICC IF IHC IHC (p) WB Rabbit IgG C-Term Log in to see JJ0942 0
7 ABIN271947 IHC (p) WB Rabbit Log in to see Polyclonal 0
7 ABIN1734281 IHC (p) ELISA WB Goat Internal Region Log in to see Polyclonal 0
7 ABIN5577912 IHC (p) WB Rabbit Log in to see Polyclonal 0
4 ABIN238438 FACS IHC (p) Mouse IgG1 Log in to see LT95 6
4 ABIN2879016 ELISA IHC IHC (p) WB Rabbit IgG AA 281-330 Log in to see Polyclonal 0

General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Epitope AA 26-173
(49), (25), (18), (15), (15), (15), (13), (12), (12), (11), (11), (9), (9), (8), (8), (7), (7), (6), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(743), (117), (97), (22), (11), (7), (5), (4), (3), (3), (3), (2), (1)
Host Rabbit
(494), (318), (24), (5), (4), (3), (3)
Clonality
Polyclonal
Conjugate This FAS antibody is un-conjugated
(74), (62), (51), (33), (19), (12), (11), (9), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(400), (359), (212), (204), (103), (93), (87), (83), (52), (41), (22), (20), (11), (8), (8), (7), (7), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 19 references available
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Product Details anti-FAS Antibody

Target Details FAS Application Details Handling References for anti-FAS antibody (ABIN3042387) Images
Purpose Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 6(FAS) detection. Tested with WB, IHC-P in Human.
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 6(FAS) detection. Tested with WB, IHC-P in Human.
Gene Name: Fas cell surface death receptor
Protein Name: Tumor necrosis factor receptor superfamily member 6
Purification Immunogen affinity purified.
Immunogen E.coli-derived human Fas recombinant protein (Position: Q26-N173). Human Fas shares 55% and 59% amino acid (aa) sequences identity with mouse and rat Fas, respectively.
Isotype IgG
Plasmids, Primers & others

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling References for anti-FAS antibody (ABIN3042387) Images back to top
Antigen
Alternative Name FAS (FAS Antibody Abstract)
Background FAS(also known as surface antigen APO1 or CD95) is a member of the tumour-necrosis receptor factor family of death receptors. It acts as an inducer of both neurite growth in vitro and accelerated recovery after nerve injury in vivo. FAS antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. The FAS antigen shows structural homology with a number of cell surface receptors, including tumor necrosis factor(TNF) receptors and the low-affinity nerve growth factor receptor(NGFR) and it is mapped to 10q24.1. The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis.

Synonyms: ALPS 1A antibody|ALPS1A antibody|APO 1 antibody|Apo 1 antigen antibody|APO 1 cell surface antigen antibody|Apo-1 antigen antibody|APO1 antibody|Apo1 antigen antibody|APO1 cell surface antigen antibody|Apoptosis antigen 1 antibody|Apoptosis mediating surface antigen FAS antibody|Apoptosis-mediating surface antigen FAS antibody|APT 1 antibody|APT1 antibody|CD 95 antibody|CD 95 antigen antibody|CD95 antibody|CD95 antigen antibody|Delta Fas antibody|Delta Fas/APO 1/CD95 antibody|Delta Fas/APO1/CD95 antibody|Fas (TNF receptor superfamily, member 6) antibody|FAS 1 antibody|FAS 827dupA antibody|Fas AMA antibody|FAS antibody|FAS Antigen antibody|Fas cell surface death receptor antibody|FAS1 antibody|FASLG receptor antibody|FASTM antibody|sFAS antibody|Surface antigen APO1 antibody|TNF receptor superfamily, member 6 antibody|TNFRSF 6 antibody|TNFRSF6 antibody|TNR6_HUMAN antibody|Tumor necrosis factor receptor superfamily member 6 antibody
Gene ID 355
UniProt P25445
Pathways p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling References for anti-FAS antibody (ABIN3042387) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Fas is approximately 0.2 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details References for anti-FAS antibody (ABIN3042387) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-FAS antibody (ABIN3042387)

Product Details anti-FAS Antibody Target Details FAS Application Details Handling Images back to top
Product cited in:

Gao, Liu, Huang, Zhang, Mei, Wang, Gong, Zhao, Xie, Ma, Qian: "HSP70 inhibits stress-induced cardiomyocyte apoptosis by competitively binding to FAF1." in: Cell stress & chaperones, Vol. 20, Issue 4, pp. 653-61, 2016

Liu, Xu, Zhao, Xia, Song, Gu, Liu, Bian, Yuan, Liu: "Osteoprotegerin Induces Apoptosis of Osteoclasts and Osteoclast Precursor Cells via the Fas/Fas Ligand Pathway." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142519, 2016

Li, Xu, Jiang, Zhao, Ge, Zheng: "Significance of Fas and FasL protein expression in cardiac carcinoma and local lymph node tissues." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 11915-20, 2016

Li, Wu, Sun, Zhao, Liu, Zhang: "Croton Tiglium Extract Induces Apoptosis via Bax/Bcl-2 Pathways in Human Lung Cancer A549 Cells" in: Asian Pacific journal of cancer prevention : APJCP, Vol. 17, Issue 11, pp. 4893-4898, 2016

Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: "A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes." in: Natural products and bioprospecting, Vol. 5, Issue 3, pp. 159-66, 2015

Kan, Zhou, Jin, Yang: "Effects of PDTC on NF-?B expression and apoptosis in rats with severe acute pancreatitis-associated lung injury." in: International journal of clinical and experimental medicine, Vol. 8, Issue 3, pp. 3258-70, 2015

Liu, Su, Zhang, Zhang, Wang, Qian: "Rhodiola rosea suppresses thymus T-lymphocyte apoptosis by downregulating tumor necrosis factor-?-induced protein 8-like-2 in septic rats." in: International journal of molecular medicine, Vol. 36, Issue 2, pp. 386-98, 2015

Jiang, Li, Zhou, Wang, Zhang, Wang: "Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways." in: International journal of molecular medicine, Vol. 33, Issue 5, pp. 1298-304, 2014

Wu, Hu, Liu, Cao, Xu, Li, Li: "Nature and mechanisms of hepatocyte apoptosis induced by D-galactosamine/lipopolysaccharide challenge in mice." in: International journal of molecular medicine, Vol. 33, Issue 6, pp. 1498-506, 2014

Weng, Xie, Yi, Huang, Luo, Du, Chen, Liu, Chen, Chen: "Loss of Vhl in cartilage accelerated the progression of age-associated and surgically induced murine osteoarthritis." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 22, Issue 8, pp. 1197-205, 2014

Liu, Shan, Dong, Liu, Ma, Liu: "Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury." in: World journal of gastroenterology, Vol. 19, Issue 4, pp. 492-502, 2013

Li, Xu, Chu, Gao, Wang, Nie, Yang, Lv: "Molecular mechanism of inhibitory effects of CD59 gene on atherosclerosis in ApoE (-/-) mice." in: Immunology letters, Vol. 156, Issue 1-2, pp. 68-81, 2013

Ma, Zhang, Zhang, Yang, Meng, Zhang, Zhou: "The effect of esculentoside A on lupus nephritis-prone BXSB mice." in: Archives of medical science : AMS, Vol. 9, Issue 2, pp. 354-60, 2013

Liu, Liu, Li, Wang, Zhao: "Hydrogen sulfide donor regulates alveolar epithelial cell apoptosis in rats with acute lung injury." in: Chinese medical journal, Vol. 126, Issue 3, pp. 494-9, 2013

Li, Xia, Wang, Li, Xue, Wu, Ye: "Relationship between aberrant methylation of FAS promoter and biological behavior of bladder urothelial carcinoma." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 31, Issue 6, pp. 794-8, 2011

Li, Peng, Li, Liu, Liang, Zhang: "Clinical significance of Fas and FasL protein expression in gastric carcinoma and local lymph node tissues." in: World journal of gastroenterology, Vol. 16, Issue 10, pp. 1274-8, 2010

Li, Chu, Gao, Li: "Apoptotic mechanism of MCF-7 breast cells in vivo and in vitro induced by photodynamic therapy with C-phycocyanin." in: Acta biochimica et biophysica Sinica, Vol. 42, Issue 1, pp. 80-9, 2009

Liu, Zhang, Zhang, Zhu, Tian: "Construction and identification of Fas-targeting siRNA-expressing plasmid." in: Journal of Zhejiang University. Science. B, Vol. 6, Issue 7, pp. 673-7, 2005

Sadhu, Gedamu: "In vitro synthesis of double stranded RNA and measurement of thermal stability: effect of base composition, formamide and ionic strength." in: Biochemistry international, Vol. 14, Issue 6, pp. 1015-22, 1988

Images

Product Details anti-FAS Antibody Target Details FAS Application Details Handling References for anti-FAS antibody (ABIN3042387) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) (AA 26-173) antibody (ABIN3042387) Anti- FAS Picoband antibody, IHC(P) IHC(P): Human Lung Cancer Tissue
Western Blotting (WB) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) (AA 26-173) antibody (ABIN3042387) Anti- FAS Picoband antibody, Western blotting All lanes: Anti FAS at 0.5ug/ml Lane 1...
Western Blotting (WB) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) (AA 26-173) antibody (ABIN3042387) Anti- FAS Picoband antibody, Western blotting All lanes: Anti FAS at 0.5ug/ml WB: Re...