anti-Human FAS antibody for Western Blotting

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • ALPS1A
  • APO-1
  • APT1
  • CD95
  • FAS1
  • FASTM
  • TNFRSF6
  • AI196731
  • APO1
  • TNFR6
  • Tnfrsf6
  • lpr
  • Fas cell surface death receptor
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  • Fas (TNF receptor superfamily member 6)
  • FAS
  • YWHAZ
  • Fas
  • fas
Reactivity
Human
662
113
95
11
7
5
4
4
3
3
2
2
1
Host
Mouse
420
312
24
5
4
3
3
Clonality
Monoclonal
Conjugate
This FAS antibody is un-conjugated
70
59
48
30
16
9
7
6
5
5
5
4
4
4
4
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), ELISA, Western Blotting (WB)
341
336
208
170
88
75
75
75
52
41
20
18
12
8
7
6
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
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Catalog No. ABIN969518
$ 430.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
30.554138 ABIN969519 FACS ELISA WB Mouse IgG1 Log in to see 4F8D6 2
26.054138 ABIN3020739 WB Rabbit IgG Log in to see Polyclonal 0
24.305216 ABIN3042387 IHC (p) WB Rabbit IgG AA 26-173 Log in to see Polyclonal 19
20.054138 ABIN3183794 ELISA IHC WB Rabbit IgG C-Term Log in to see Polyclonal 0
20.054138 ABIN3181066 ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 0
19.805216 ABIN1872658 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
19.805216 ABIN1845668 ELISA FACS IF/ICC WB Mouse IgG1 Log in to see 0
17.054138 ABIN3184594 ELISA IF WB Rabbit IgG Ser15 Log in to see Polyclonal 0
17.054138 ABIN3023511 WB Rabbit IgG pTyr291 Log in to see Polyclonal 0
17.054138 ABIN632316 WB Rabbit Log in to see Polyclonal 0
17.054138 ABIN929135 WB Rabbit N-Term Log in to see Polyclonal 0
17.054138 ABIN5664114 IHC WB Rabbit Log in to see Polyclonal 0
16.805216 ABIN4880717 ELISA FACS ICC WB Mouse IgG1 Log in to see 4F8H6 0
16.805216 ABIN1106616 EIA FACS IF WB Mouse IgG1 Log in to see 4F8H6 2
16 ABIN2988496 IHC WB Rabbit IgG Log in to see Polyclonal 0
13.805215 ABIN4880718 ELISA FACS WB Mouse IgG1 Log in to see 4F8D6 0
13.805215 ABIN1845671 FACS ELISA WB Mouse IgG1 Log in to see 0
13.805215 ABIN1106617 EIA FACS WB Mouse IgG1 Log in to see 4F8D6 2
13.805215 ABIN513435 IP ELISA WB Mouse IgG1 kappa AA 20-119 Log in to see 5B4 0
13.805215 ABIN559907 PLA ELISA WB Mouse IgG2a kappa AA 20-119 Log in to see 2G3 0

General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Reactivity Human
(662), (113), (95), (11), (7), (5), (4), (4), (3), (3), (2), (2), (1)
Host Mouse
(420), (312), (24), (5), (4), (3), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FAS antibody is un-conjugated
(70), (59), (48), (30), (16), (9), (7), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), ELISA, Western Blotting (WB)
(341), (336), (208), (170), (88), (75), (75), (75), (52), (41), (20), (18), (12), (8), (7), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-FAS Antibody

Target Details FAS Application Details Handling References for anti-FAS antibody (ABIN969518) Images
Purification Purified
Immunogen Purified recombinant fragment of human FAS expressed in E. Coli.
Clone 4F8H6
Isotype IgG1
Plasmids, Primers & others

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling References for anti-FAS antibody (ABIN969518) Images back to top
Antigen
Alternative Name FAS (FAS Antibody Abstract)
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
Molecular Weight 37.7 kDa
Gene ID 355
HGNC 355
Pathways p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling References for anti-FAS antibody (ABIN969518) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details References for anti-FAS antibody (ABIN969518) Images back to top
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-FAS antibody (ABIN969518)

Product Details anti-FAS Antibody Target Details FAS Application Details Handling Images back to top
Product cited in:

Liu, Jung, Orlandi, Yeh, Lin, Shiu, Wu, Chu, Lin, Chu: "The Fas-mediated apoptotic pathway in cardiac myxoma." in: International journal of surgical pathology, Vol. 18, Issue 6, pp. 493-8, 2010

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009

Images

Product Details anti-FAS Antibody Target Details FAS Application Details Handling References for anti-FAS antibody (ABIN969518) back to top
Supplier Images
ELISA image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN969518) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN969518) Figure 2: Flow cytometric analysis of Hela cells using FAS mouse mAb (green) and nega...
Immunocytochemistry (ICC) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN969518) Figure 3: Immunofluorescence analysis of Hela cells using FAS mouse mAb (green) . Blu...
Western Blotting (WB) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN969518) Figure 4: Western blot analysis using FAS mouse mAb against Hela (1), Jurkat (2) cell...
Western Blotting (WB) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN969518) Figure 5: Western blot analysis using FAS mAb against human FAS (AA: 87-278) recombin...