anti-Human FAS antibody for Western Blotting

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • ALPS1A
  • APO-1
  • APT1
  • CD95
  • FAS1
  • FASTM
  • TNFRSF6
  • AI196731
  • APO1
  • TNFR6
  • Tnfrsf6
  • lpr
  • Fas cell surface death receptor
  • Fas (TNF receptor superfamily member 6)
  • FAS
  • Fas
  • fas
Epitope
Middle Region
46
25
18
16
15
15
15
15
12
11
11
10
9
9
8
8
7
7
6
5
5
5
5
5
4
4
4
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Pig (Porcine)
660
115
95
13
11
10
4
4
3
3
3
2
1
Host
Rabbit
422
307
25
5
4
3
3
Clonality
Polyclonal
Conjugate
This FAS antibody is un-conjugated
74
63
51
31
16
9
7
6
5
5
5
4
4
4
4
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
352
330
202
181
97
80
79
73
52
44
21
19
12
8
7
6
5
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN2779353
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1681724 ABIN2787943 WB Rabbit N-Term Log in to see Polyclonal 0
3.1681724 ABIN3042387 IHC (p) WB Rabbit IgG AA 26-173 Log in to see Polyclonal 13
3.1681724 ABIN1106613 FACS Neut WB Mouse IgG1 Log in to see ZB4 11
3.1681724 ABIN2704623 IHC WB Rabbit C-Term Log in to see Polyclonal 0
3.1681724 ABIN783308 WB Rabbit AA 323-327 Log in to see Polyclonal 3
3.1681724 ABIN266061 IHC (p) IHC WB Rabbit Log in to see Polyclonal 3
3.1681724 ABIN411481 IHC WB Rabbit IgG Log in to see Polyclonal 0
3.1681724 ABIN1532613 IF ELISA WB Rabbit IgG AA 257-306 Log in to see Polyclonal 2
3.1681724 ABIN652469 IF WB Rabbit Ig Fraction AA 185-211, Center Log in to see Polyclonal 3
3.1681724 ABIN2464254 ELISA WB Goat Internal Region Log in to see Polyclonal 0
3.1681724 ABIN1872658 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
3.1681724 ABIN1533427 IHC ELISA WB Rabbit IgG AA 281-330 Log in to see Polyclonal 0
3.1681724 ABIN969519 FACS ELISA WB Mouse IgG1 Log in to see 4F8D6 2
3.1681724 ABIN969518 ICC FACS ELISA WB Mouse IgG1 Log in to see 4F8H6 2
3.1681724 ABIN1078008 ICC IHC WB Rabbit IgG AA 26-173 Log in to see Polyclonal 1
3.1681724 ABIN1845668 ELISA FACS IF/ICC WB Mouse IgG1 Log in to see 0
3.1681724 ABIN1845671 FACS ELISA WB Mouse IgG1 Log in to see 0
3.1681724 ABIN1106616 EIA FACS IF WB Mouse IgG1 Log in to see 4F8H6 2
3.1681724 ABIN1106617 EIA FACS WB Mouse IgG1 Log in to see 4F8D6 2
3.1681724 ABIN453647 EIA WB Rabbit Middle Region Log in to see Polyclonal 2

General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Epitope Middle Region
(46), (25), (18), (16), (15), (15), (15), (15), (12), (11), (11), (10), (9), (9), (8), (8), (7), (7), (6), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Pig (Porcine)
(660), (115), (95), (13), (11), (10), (4), (4), (3), (3), (3), (2), (1)
Host Rabbit
(422), (307), (25), (5), (4), (3), (3)
Clonality
Polyclonal
Conjugate This FAS antibody is un-conjugated
(74), (63), (51), (31), (16), (9), (7), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(352), (330), (202), (181), (97), (80), (79), (73), (52), (44), (21), (19), (12), (8), (7), (6), (5), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-FAS Antibody

Target Details FAS Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN976696
Sequence KKEAYDTLIK DLKKANLCTL AEKIQTIILK DITSDSENSN FRNEIQSLV
Predicted Reactivity Human: 100%, Pig: 80%
Characteristics This is a rabbit polyclonal antibody against FAS. It was validated on Western Blot.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human FAS
Plasmids, Primers & others

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling Images back to top
Antigen
Alternative Name FAS (FAS Antibody Abstract)
Background FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. At least eight alternatively spliced transcript variants encoding seven distinct isoforms have been described. The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
Alias Symbols: ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6
Protein Interaction Partner: FADD, CAV1, FAS, APOA5, TMX1, UBQLN1, MBD4, TP63, TCAP, BAG6, UBC, HNRNPC, GADD45A, CCND3, ATP6V0B, SQSTM1, Ube2i, PRAM1, RARA, PML, DAXX, FASLG, TRADD, MAP3K5, BMX, Traf1, FAF1, FAF2, TRAF3, KRIT1, TNF, BRE, LRIF1, FEM1B, FBF1, FAIM2, CASP8AP2, C14orf1,
Protein Size: 335
Molecular Weight 36 kDa
Gene ID 355
NCBI Accession NM_000043, NP_000034
UniProt P25445
Pathways p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 335 AA

Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-FAS Antibody Target Details FAS Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) (Middle Region) antibody (ABIN2779353) WB Suggested Anti-FAS Antibody Titration: 0.2-1 ug/ml Positive Control: Human Liver