anti-Human SERPINE1 antibody for Neutralization

Recommended SERPINE1 Antibody

Antigen
serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) Antibodies
  • PAI
  • PAI-1
  • PAI1
  • PLANH1
  • SERPINE1
  • si:ch211-138a11.1
  • Planh1
  • PAI1A
  • Pai1
  • Pai1aa
  • Planh
  • RATPAI1A
  • serpin family E member 1
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • serine (or cysteine) peptidase inhibitor, clade E, member 1
  • SERPINE1
  • serpine1.L
  • serpine1
  • Serpine1
Reactivity
Human
357
127
118
42
17
11
7
6
5
4
3
2
2
1
1
Host
Rabbit
267
129
52
28
2
1
1
Clonality
Polyclonal
Conjugate
This SERPINE1 antibody is un-conjugated
48
31
16
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
Application
ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut), Western Blotting (WB)
334
217
141
54
43
30
26
25
24
19
17
9
9
6
6
6
4
4
4
4
3
2
1
1
1
Options

Available images

Catalog No. ABIN1104210
$ 639.83
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN1983426 Neut WB Mouse IgG1 AA 21-402 MM0542-12V3 0
1 ABIN5690557 ELISA Neut WB Rabbit Polyclonal 0

General

Antigen serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) Antibodies
Reactivity Human
(357), (127), (118), (42), (17), (11), (7), (6), (5), (4), (3), (2), (2), (1), (1)
Host Rabbit
(267), (129), (52), (28), (2), (1), (1)
Clonality
Polyclonal
Conjugate This SERPINE1 antibody is un-conjugated
(48), (31), (16), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1)
Application ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut), Western Blotting (WB)
(334), (217), (141), (54), (43), (30), (26), (25), (24), (19), (17), (9), (9), (6), (6), (6), (4), (4), (4), (4), (3), (2), (1), (1), (1)
Supplier

Product Details anti-SERPINE1 Antibody

Target Details SERPINE1 Application Details Handling Images
Brand IHC-plus™
Specificity Human PAI-1
Purification Immunoaffinity purified
Immunogen E.coli derived recombinant Human PAI-1.

Type of Immunogen: Cell extract
Isotype IgG
Plasmids, Primers & others

Target Details SERPINE1

Product Details anti-SERPINE1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SERPINE1 / PAI-1 (SERPINE1 Antibody Abstract)
Background Name/Gene ID: SERPINE1
Family: Serine Protease Inhibitor

Synonyms: SERPINE1, PAI1, PLANH1, PAI-1, Serpin E1
Gene ID 5054
UniProt P05121
Pathways p53 Signaling, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration

Application Details

Product Details anti-SERPINE1 Antibody Target Details SERPINE1 Handling Images back to top
Application Notes Approved: ELISA, IHC, IHC-P (5 μg/mL), Neut (15 μg/mL), WB (0.1 - 0.2 μg/mL)

Usage: Immunohistochemistry: LS-B7483 in an IHC-plus antibody, validated by our pathologists for use in IHC against formalin-fixed, paraffin-embedded human tissues (IHC validation procedure). A concentration of 5 μg/mL is recommended. Neutralization: To yield one-half maximal inhibition [ND] of the biological activity of hPAI-1 (4.5 μg/mL), a concentration of at least 15 μg/mL of this antibody is required. ELISA: To detect hPAI-1 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human PAI-1 (LS-C104564) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant hPAI-1. Western Blot: To detect hPAI-1 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hPAI-1 is 1.5-3 ng/lane, under either reducing or non-reducing conditions.
Comment

Target Species of Antibody: Human

Restrictions For Research Use only

Handling

Product Details anti-SERPINE1 Antibody Target Details SERPINE1 Application Details Images back to top
Format Lyophilized
Reconstitution Sterile water
Concentration Lot specific
Buffer Lyophilized from PBS,  pH 7.2
Handling Advice Avoid freeze/thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Store Lyophilized at room temperature up to 1 month
Reconstituted for up to 2 weeks at 2-8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles.

Images

Product Details anti-SERPINE1 Antibody Target Details SERPINE1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) antibody (ABIN1104210) Anti-SERPINE1 / PAI-1 antibody IHC staining of human vascular endothelium. Immunohist...
Immunohistochemistry (IHC) image for anti-serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) antibody (ABIN1104210) Anti-SERPINE1 / PAI-1 antibody IHC of human vascular endothelium. Immunohistochemistr...