Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) Peptide
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- Target See all MTHFD1 products
- MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- CMAKTHLSLS HNPEQKGVPT GFILPIRDIR ASVGAGFLYP LVGTMSTMPG
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MTHFD1 antibody,
Alternative Names: MTHFD1 control peptide, MTHFD1 antibody Blocking Peptide, Anti-MTHFD1 Blocking Peptide, Methylenetetrahydrofolate Dehydrogenase Blocking Peptide, Nadp+ Dependent 1 Methenyltetrahydrofolate Cyclohydrolase Formyltetrahydrofolate Synthetase Blocking Peptide, MTHFC Blocking Peptide, MTHFD Blocking Peptide, MTHFD1, MTHFD-1, MTHFD 1, MTHFD-1 Blocking Peptide, MTHFD 1 Blocking Peptide - Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
- Synonyms
- MTHFC Peptide, MTHFD Peptide, Tb07.27M11.970 Peptide, Dcs Peptide, E430024A07Rik Peptide, Mthfd Peptide, GB13160 Peptide, cb325 Peptide, fc29f07 Peptide, mthfd1 Peptide, wu:fc29f07 Peptide, zgc:55597 Peptide, methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Peptide, C-1-tetrahydrofolate synthase, cytoplasmic Peptide, putative C-1-tetrahydrofolate synthase, cytoplasmic Peptide, putative C-1-tetrahydrofolate synthase,cytoplasmic Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b Peptide, c-1-tetrahydrofolate synthase, cytoplasmic Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase L homeolog Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase Peptide, MTHFD1 Peptide, Mthfd1 Peptide, Tc00.1047053509509.20 Peptide, Tc00.1047053511741.50 Peptide, Tc00.1047053511517.60 Peptide, Tc00.1047053508207.240 Peptide, Tb927.7.1600 Peptide, LINJ_26_0310 Peptide, LBRM_26_0350 Peptide, LMJF_26_0320 Peptide, mthfd1l Peptide, LOC550749 Peptide, mthfd1b Peptide, Tsp_00651 Peptide, mthfd1.L Peptide, mthfd1 Peptide, LOC589933 Peptide, LOC100634307 Peptide
- Background
- MTHFD1 possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.
- Molecular Weight
- 101 kDa
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