Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) Peptide
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- Target See all KCNQ2 products
- KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- YRGWRGRLKF ARKPFCVIDI MVLIASIAVL AAGSQGNVFA TSALRSLRFL
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of KCNQ2 antibody,
Alternative Names: KCNQ2 control peptide, KCNQ2 antibody Blocking Peptide, Anti-KCNQ2 Blocking Peptide, Potassium Voltage-Gated Channel Kqt-Like Subfamily Member 2 Blocking Peptide, BFNC Blocking Peptide, EBN Blocking Peptide, EBN1 Blocking Peptide, ENB1 Blocking Peptide, HNSPC Blocking Peptide, KCNA11 Blocking Peptide, KV7.2 Blocking Peptide, KVEBN1 Blocking Peptide, KCNQ2, KCNQ-2, KCNQ 2, KCNQ-2 Blocking Peptide, KCNQ 2 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
- Synonyms
- BFNC Peptide, BFNS1 Peptide, EBN Peptide, EBN1 Peptide, EIEE7 Peptide, ENB1 Peptide, HNSPC Peptide, KCNA11 Peptide, KV7.2 Peptide, KVEBN1 Peptide, KQT2 Peptide, Nmf134 Peptide, mKQT2.3 Peptide, mKQT2.4 Peptide, zgc:171872 Peptide, potassium voltage-gated channel subfamily Q member 2 Peptide, potassium voltage-gated channel, subfamily Q, member 2 Peptide, potassium voltage-gated channel subfamily KQT member 2 Peptide, potassium voltage-gated channel, KQT-like subfamily, member 2a Peptide, KCNQ2 Peptide, Kcnq2 Peptide, LOC100537363 Peptide, kcnq2a Peptide
- Background
- The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).
- Molecular Weight
- 93 kDa
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