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Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) Peptide

KCNQ2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN939302
  • Target See all KCNQ2 products
    KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 11
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    IDIMVLIASI AVLAAGSQGN VFATSALRSL RFLQILRMIR MDRRGGTWKL
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of KCNQ2 antibody,
    Alternative Names: KCNQ2 control peptide, KCNQ2 antibody Blocking Peptide, Anti-KCNQ2 Blocking Peptide, Potassium Voltage-Gated Channel Kqt-Like Subfamily Member 2 Blocking Peptide, BFNC Blocking Peptide, EBN Blocking Peptide, EBN1 Blocking Peptide, ENB1 Blocking Peptide, HNSPC Blocking Peptide, KCNA11 Blocking Peptide, KV7.2 Blocking Peptide, KVEBN1 Blocking Peptide, KCNQ2, KCNQ-2, KCNQ 2, KCNQ-2 Blocking Peptide, KCNQ 2 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
    Synonyms
    BFNC Peptide, BFNS1 Peptide, EBN Peptide, EBN1 Peptide, EIEE7 Peptide, ENB1 Peptide, HNSPC Peptide, KCNA11 Peptide, KV7.2 Peptide, KVEBN1 Peptide, KQT2 Peptide, Nmf134 Peptide, mKQT2.3 Peptide, mKQT2.4 Peptide, zgc:171872 Peptide, potassium voltage-gated channel subfamily Q member 2 Peptide, potassium voltage-gated channel, subfamily Q, member 2 Peptide, potassium voltage-gated channel subfamily KQT member 2 Peptide, potassium voltage-gated channel, KQT-like subfamily, member 2a Peptide, KCNQ2 Peptide, Kcnq2 Peptide, LOC100537363 Peptide, kcnq2a Peptide
    Background
    The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).
    Molecular Weight
    44 kDa
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