Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) (Middle Region) Peptide
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- Target See all CBFA2T2 products
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CBFA2T2 antibody (Catalog #: ARP38559_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
- Synonyms
- MTGR1 Peptide, A430091M07 Peptide, C330013D05Rik Peptide, Cbfa2t2h Peptide, EHT Peptide, ZMYND3 Peptide, p85 Peptide, XETOR Peptide, cbfa2t2-a Peptide, CBFA2/RUNX1 translocation partner 2 Peptide, core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) Peptide, CBFA2/RUNX1 translocation partner 2 L homeolog Peptide, Cbfa2t2 Peptide, CBFA2T2 Peptide, cbfa2t2.L Peptide
- Background
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In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-
Alias Symbols: DKFZp313F2116, EHT, MTGR1, ZMYND3, p85
Protein Interaction Partner: RUNX1T1,ATN1,CBFA2T3,CBFB,MDFI,NCOR1,NCOR2,RERE,RUNX1,SIN3A,WDYHV1,CBFA2T3,MDFI,RUNX1,RUNX1T1,TAL1,WDYHV1
Protein Size: 604 - Molecular Weight
- 67 kDa
- Gene ID
- 9139
- NCBI Accession
- NM_013277, NP_005084
- UniProt
- O43439
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