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Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Peptide Peptide

AIFM1 Origin: Human Source: Synthetic BP, IHC, WB
Catalog No. ABIN981497
$99.00
Plus shipping costs $45.00
100 μg
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  • Target
    AIFM1
    Origin
    Human
    Source
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PDCD8 antibody (Catalog #: AVARP00028_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    AIFM1
    Synonyms
    AIF, CMTX4, COWCK, COXPD6, PDCD8, CG7263, DmAIF, Dmel\\CG7263, GB16024, DDBDRAFT_0187853, DDBDRAFT_0191137, DDB_0187853, DDB_0191137, aif, pdcd8, AIFM1, PCD8, AIFsh2, Hq, Pdcd8, mAIF, Aif, zgc:91994, apoptosis inducing factor mitochondria associated 1, allograft inflammatory factor 1, Apoptosis inducing factor, apoptosis-inducing factor 1, mitochondrial, apoptosis inducing factor, apoptosis inducing factor, mitochondria associated 1, apoptosis-inducing factor, mitochondrion-associated, 1, apoptosis-inducing factor, mitochondrion-associated 1, AIFM1, AIF1, AIF, LOC412212, aif, aifm1, Aifm1
    Background
    AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, AIFM1 induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.

    Alias Symbols: RP3-438D16.2, AIF, MGC111425, PDCD8, COXPD6

    Protein Interaction Partner: C4orf14,CASP3,EIF3G,HSPA1A,HSPA1B,SETDB1,STC2,TSC22D4,WWC1,BRF2,C20orf24,HSPA1A,MLF2,MLH1,PELO,PMS2,PTP4A3,SETDB1,STC2,UBC,XIAP

    Protein Size: 609
    Molecular Weight
    66 kDa
    Gene ID
    9131
    NCBI Accession
    NM_145812, NP_665811
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