Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) Peptide
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- Target See all SREBF1 products
- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SREBF1 antibody (Catalog #: ARP37145_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
- Synonyms
- SREBP-1c Peptide, SREBP1 Peptide, bHLHd1 Peptide, ADD-1 Peptide, ADD1 Peptide, D630008H06 Peptide, SREBP-1 Peptide, SREBP-1a Peptide, SREBP1c Peptide, Srebp1 Peptide, SCREBP1 Peptide, SREBP-1C Peptide, SREBF1 Peptide, srebp1 Peptide, sterol regulatory element binding transcription factor 1 Peptide, sterol regulatory element binding transcription factor 1 L homeolog Peptide, sterol regulatory element binding protein-1 Peptide, Sterol regulatory element Binding Protein Peptide, SREBF1 Peptide, Srebf1 Peptide, srebf1.L Peptide, SREBP-1 Peptide, srebf1 Peptide, sbp-1 Peptide
- Background
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Srebf1 is transcriptional activator that binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Srebf1 also binds to an E-box motif (5'-ATCACGTGA-3'). Srebf1 regulates the transcription of genes for sterol biosynthesis and the LDL receptor gene.
Alias Symbols: ADD1, ADD-1, SREBP1, bHLHd1, SREBP-1, SREBP1c, SREBP-1a, SREBP-1c, D630008H06
Protein Interaction Partner: Ppargc1b
Protein Size: 1134 - Molecular Weight
- 125 kDa
- Gene ID
- 20787
- NCBI Accession
- NM_011480, NP_035610
- UniProt
- Q9WTN3
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