anti-Mouse (Murine) CDK2 antibody for Western Blotting

Recommended CDK2 Antibody (supplied by: Log in to see )

Antigen
Cyclin-Dependent Kinase 2 (CDK2) Antibodies
  • p33(CDK2)
  • cinp
  • CINP
  • MGC84068
  • A630093N05Rik
  • wu:fa10c02
  • zgc:56598
  • zgc:77684
  • eg1
  • CDKN2
  • cdk2L
  • cyclin dependent kinase 2
  • cyclin dependent kinase 2 interacting protein
  • cyclin-dependent kinase 2 interacting protein S homeolog
  • cyclin-dependent kinase 2
  • cyclin-dependent kinase 2 S homeolog
  • CDK2
  • cinp
  • CINP
  • cinp.S
  • Cdk2
  • cdk2
  • cdk2.S
Epitope
AA 81-298
68
53
36
15
14
10
9
8
8
7
6
6
5
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
427
267
174
62
19
18
15
15
14
13
13
11
8
5
4
4
3
1
Host
Rabbit
327
158
1
Clonality
Polyclonal
Conjugate
This CDK2 antibody is un-conjugated
25
18
16
12
12
8
7
7
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
419
216
132
93
79
71
52
39
33
19
11
8
3
3
3
2
2
1
1
Options
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Catalog No. ABIN3043472
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2286417 ABIN2779325 IHC WB Rabbit Middle Region Log in to see Polyclonal 1
3.2286417 ABIN967777 BI IP IHC WB Mouse IgG2a AA 109-298 Log in to see 55-Cdk2 5
3.2286417 ABIN2792150 IHC WB Rabbit C-Term Log in to see Polyclonal 1
3.2286417 ABIN2705842 IHC WB Rabbit Center Log in to see Polyclonal 0
3.2286417 ABIN2705841 IHC WB Rabbit pSer160 Log in to see Polyclonal 0
3.2286417 ABIN967634 IP WB Rabbit Ig Fraction AA 287-298 Log in to see Polyclonal 6
3.2286417 ABIN4297023 WB Rabbit Log in to see Polyclonal 5
3.2286417 ABIN1533672 IF ELISA WB Rabbit IgG AA 231-280 Log in to see Polyclonal 1
3.2286417 ABIN967776 BI IP IHC WB Mouse IgG2a AA 109-298 Log in to see 55-Cdk2 5
3.2286417 ABIN1532828 ELISA WB Rabbit IgG AA 131-180 Log in to see Polyclonal 0
3.2286417 ABIN1531798 IHC ELISA WB Rabbit IgG AA 127-176, pThr160 Log in to see Polyclonal 0
3.2286417 ABIN1106646 WB Mouse IgG1 Log in to see 8A12 4
3.2286417 ABIN969506 ICC FACS IHC ELISA WB Mouse IgG1 Log in to see 1A6 1
3.2286417 ABIN3183838 ELISA IF IHC WB Rabbit IgG C-Term Log in to see Polyclonal 0
3.2286417 ABIN3183839 ELISA WB Rabbit IgG Ser226 Log in to see Polyclonal 0
3.2286417 ABIN3181959 ELISA IHC WB Rabbit IgG pThr160 Log in to see Polyclonal 0
3.2286417 ABIN1870053 IHC WB Rabbit IgG pThr160 Log in to see Polyclonal 0
3.2286417 ABIN1043673 IHC WB Rabbit C-Term Log in to see Polyclonal 1
3.2286417 ABIN251166 CyTOF ELISA FACS IP WB Mouse IgG2a Log in to see AN4-3 1
3.2286417 ABIN1106645 EIA FACS IF IHC (p) WB Mouse IgG1 Log in to see 1A6 1

General

Antigen Cyclin-Dependent Kinase 2 (CDK2) Antibodies
Epitope AA 81-298
(68), (53), (36), (15), (14), (10), (9), (8), (8), (7), (6), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(427), (267), (174), (62), (19), (18), (15), (15), (14), (13), (13), (11), (8), (5), (4), (4), (3), (1)
Host Rabbit
(327), (158), (1)
Clonality
Polyclonal
Conjugate This CDK2 antibody is un-conjugated
(25), (18), (16), (12), (12), (8), (7), (7), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(419), (216), (132), (93), (79), (71), (52), (39), (33), (19), (11), (8), (3), (3), (3), (2), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-CDK2 Antibody

Target Details CDK2 Application Details Handling References for anti-CDK2 antibody (ABIN3043472) Images
Purpose Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 2(CDK2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 2(CDK2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: cyclin-dependent kinase 2
Protein Name: Cyclin-dependent kinase 2
Purification Immunogen affinity purified.
Immunogen E.coli-derived human Cdk2 recombinant protein (Position: E81-L298). Human Cdk2 shares 98.6% amino acid (aa) sequence identity with rat Cdk2.
Isotype IgG

Target Details CDK2

Product Details anti-CDK2 Antibody Application Details Handling References for anti-CDK2 antibody (ABIN3043472) Images back to top
Antigen
Alternative Name CDK2 (CDK2 Antibody Abstract)
Background CDK2, Cyclin-Dependent Kinase2, is also known as P33. The CDK2 protein was highly homologous to p34(CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting that CDK2 is the human homolog of Eg1. The CDK2 gene is mapped to 12q13, the same region to which the CDK4 gene maps. Human cyclin A binds independently to 2 kinases, p34(cdc2) or p33. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/cyclin A but not with p34(cdc2)/cyclin A. The gene for p33 shares 65 % sequence identity with p34(cdc2). P33(cdk2) plays a unique role in cell cycle regulation of vertebrate cells.

Synonyms: Cdc2 related protein kinase antibody|cdc2-related protein kinase antibody|Cdk 2 antibody| CDK2 antibody|CDK2_HUMAN antibody|Cell devision kinase 2 antibody|Cell division kinase 2 antibody|Cell division protein kinase 2 antibody|Cyclin dependent kinase 2 antibody|cyclin dependent kinase 2-alpha antibody|Cyclin-dependent kinase 2 antibody|p33 protein kinase antibody|p33(CDK2) antibody
Gene ID 1017
UniProt P24941
Pathways PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA

Application Details

Product Details anti-CDK2 Antibody Target Details CDK2 Handling References for anti-CDK2 antibody (ABIN3043472) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Handling

Product Details anti-CDK2 Antibody Target Details CDK2 Application Details References for anti-CDK2 antibody (ABIN3043472) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-CDK2 antibody (ABIN3043472)

Product Details anti-CDK2 Antibody Target Details CDK2 Application Details Handling Images back to top
Product cited in:

Ren, Huang, Xu, Yang, Yang, Hu: "Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells." in: Anti-cancer drugs, Vol. 26, Issue 6, pp. 599-611, 2015

Zhou, Lu, Liu, Guo, Liu, Zhou, Yang, Mi, Xu: "Platycodin D induces tumor growth arrest by activating FOXO3a expression in prostate cancer in vitro and in vivo." in: Current cancer drug targets, Vol. 14, Issue 9, pp. 860-71, 2015

Zhao, Li, Gao, Wang, Yan, Zhan, Liu, Mao, Chen, Wang et al.: "Design, synthesis and biological evaluation of N-alkyl or aryl substituted isoindigo derivatives as potential dual cyclin-dependent kinase 2 (CDK2)/glycogen synthase kinase 3? (GSK-3?) ..." in: European journal of medicinal chemistry, Vol. 86, pp. 165-74, 2014

Cheng, Chen, Wang, Ding, Shi: "The effects of urokinase-type plasminogen activator (uPA) on cell proliferation and phenotypic transformation of rat mesangial cells induced by high glucose." in: Diabetes research and clinical practice, Vol. 103, Issue 3, pp. 489-95, 2014

Ye, Chen, Chen, Xie, Yang, Lou, Yu: "XJW20, a novel oxoindole derivative, induces G2/M arrest and apoptosis selectively in K562 leukemia cell line." in: Chemico-biological interactions, Vol. 183, Issue 1, pp. 133-41, 2009

Images

Product Details anti-CDK2 Antibody Target Details CDK2 Application Details Handling References for anti-CDK2 antibody (ABIN3043472) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 81-298) antibody (ABIN3043472) Anti- Cdk2 Picoband antibody,IHC(P) IHC(P): Human Lung Cancer Tissue
Western Blotting (WB) image for anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 81-298) antibody (ABIN3043472) anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 81-298) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 81-298) antibody (ABIN3043472) Anti- Cdk2 Picoband antibody,IHC(P) IHC(P): Mouse Testis Tissue
Immunohistochemistry (IHC) image for anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 81-298) antibody (ABIN3043472) Anti- Cdk2 Picoband antibody,IHC(P) IHC(P): Rat Testis Tissue