anti-Human CHUK antibody for Enzyme Immunoassay

Recommended CHUK Antibody (supplied by: Log in to see )

Antigen
conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) Antibodies
  • ikk
  • ikk1
  • ikka
  • ikkalpha
  • CHUK
  • IKBKA
  • IKK-alpha
  • IKK1
  • IKKA
  • NFKBIKA
  • TCF16
  • AI256658
  • Chuk1
  • Fbx24
  • Fbxo24
  • Ikka
  • zgc:56539
  • conserved helix-loop-helix ubiquitous kinase S homeolog
  • conserved helix-loop-helix ubiquitous kinase
  • chuk.S
  • CHUK
  • Chuk
  • chuk
Epitope
C-Term
48
32
17
17
15
15
11
11
10
9
9
9
8
8
7
7
7
7
6
4
4
4
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
352
152
104
20
12
11
10
7
6
5
5
4
2
1
Host
Rabbit
270
84
13
1
Clonality
Polyclonal
Conjugate
This CHUK antibody is un-conjugated
15
11
11
9
9
8
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
318
153
93
75
60
48
41
30
26
19
8
5
3
3
2
2
1
1
1
Supplier
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Catalog No. ABIN5554860
$ 469.32
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5554861 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN5554862 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN265477 EIA IHC (p) WB Rabbit Log in to see Polyclonal 0
1 ABIN1107726 EIA WB Mouse IgG1 Log in to see 7C10B6 2
1 ABIN1107728 EIA FACS IF WB Mouse IgG1 Log in to see 3G12H9 1
1 ABIN1107727 EIA WB Mouse IgG1 Log in to see 3G12 1
1 ABIN5556642 EIA IP WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN303080 EIA IF IHC (p) IP WB Rabbit Log in to see Polyclonal 0

General

Antigen conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) Antibodies
Epitope C-Term
(48), (32), (17), (17), (15), (15), (11), (11), (10), (9), (9), (9), (8), (8), (7), (7), (7), (7), (6), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(352), (152), (104), (20), (12), (11), (10), (7), (6), (5), (5), (4), (2), (1)
Host Rabbit
(270), (84), (13), (1)
Clonality
Polyclonal
Conjugate This CHUK antibody is un-conjugated
(15), (11), (11), (9), (9), (8), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(318), (153), (93), (75), (60), (48), (41), (30), (26), (19), (8), (5), (3), (3), (2), (2), (1), (1), (1)
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Product Details anti-CHUK Antibody

Target Details CHUK Application Details Handling Images
Specificity IKK alpha antibody was raised against a peptide corresponding to amino acids 716 to 734 of human IKK alpha, which differs from corresponding murine sequence by four amino acids. This antibody has no cross response to IKKb or IKKg.
Purification Affinity chromatography purified via peptide column
Immunogen Human IKK alpha (C-Terminus 1) Peptide
Isotype IgG

Target Details CHUK

Product Details anti-CHUK Antibody Application Details Handling Images back to top
Antigen
Alternative Name IKKA (CHUK Antibody Abstract)
Background Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa, and bacteria product LPS. NF-kappaB is associated with IkappaB proteins in the cell cytoplasm, which inhibit NF-kappaB activity. The long-sought IkappaB kinase (IKK), which phosphorylates IkappaB, and mediates IΚB degradation and NF-kappaB activation, was recently identified by several laboratories (1-5). IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKKalpha and IKKbeta). IKKa and IKKbeta interact with each other and both are essential for the NF-kappaB activation. IKKalpha specifically phosphorylates IkB-alpha. IKKalpha is expressed in variety of human tissues.Synonyms: CHUK, Conserved helix-loop-helix ubiquitous kinase, I kappa-B kinase alpha, I-kappa-B kinase 1, IKK-A, IKK-alpha, IKK1, IkBKA, IkappaB kinase, Inhibitor of nuclear factor kappa-B kinase subunit alpha, NFKBIKA, Nuclear factor NF-kappa-B inhibitor kinase alpha, TCF16
Gene ID 1147
NCBI Accession NP_001269
UniProt O15111
Pathways PI3K-Akt Signaling, NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades

Application Details

Product Details anti-CHUK Antibody Target Details CHUK Handling Images back to top
Application Notes ELISA. Western Blot: 1: 1000 to 1: 2000 dilution. An 85 kDa band should be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CHUK Antibody Target Details CHUK Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.