anti-Rat (Rattus) Cyclin D1 antibody for Immunocytochemistry

Recommended Cyclin D1 Antibody (supplied by: Log in to see )

Antigen
Cyclin D1 (CCND1) Antibodies
  • BCL1
  • D11S287E
  • PRAD1
  • U21B31
  • AI327039
  • CycD1
  • Cyl-1
  • bcl-1
  • cD1
  • cb161
  • cycd1
  • etID37810.7
  • fb52e01
  • fc45c08
  • fc83a12
  • id:ibd1198
  • wu:fb52e01
  • wu:fc45c08
  • wu:fc83a12
  • ccnd1b
  • prad1
  • ccnd1
  • ccnd1a
  • bcl1
  • d11s287e
  • u21b31
  • CCND1
  • cyclin D1
  • cyclin D1 S homeolog
  • cyclin D1 L homeolog
  • cyclin D2
  • CCND1
  • Ccnd1
  • ccnd1
  • ccnd1.S
  • ccnd1.L
  • CCND2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
469
235
225
44
21
20
19
17
14
4
4
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Host
Mouse
323
204
19
5
Clonality
Monoclonal
Conjugate
This Cyclin D1 antibody is un-conjugated
26
23
15
10
8
5
4
4
4
4
4
4
4
4
4
4
4
4
4
3
2
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
471
217
131
122
111
103
103
79
49
12
8
8
7
6
5
3
1
1
1
1
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Catalog No. ABIN3043639
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN4301536 ICC IF IP WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN574432 ICC IHC (fro) FACS IHC (p) IP ELISA WB Mouse IgG1 Log in to see CD1-1 0
1 ABIN1077957 ICC IHC WB Rabbit IgG AA 1-295 Log in to see Polyclonal 0
1 ABIN2471067 ICC FACS IP IHC ELISA WB Mouse IgG1 Log in to see CD1-1 0
1 ABIN1501952 ICC IHC (fro) IHC (p) WB Mouse IgG2a Log in to see CYD1 0
1 ABIN609471 ICC IHC (fro) IHC (p) WB Mouse IgG2a Log in to see 0
1 ABIN1501962 ICC IHC (fro) IHC (p) IP WB Magnetic Particles Mouse IgG2a Log in to see CY-D1 0
1 ABIN211137 Func ICC IP WB Rabbit IgG AA 285-295 Log in to see Polyclonal 0
1 ABIN200703 ICC IP WB Mouse IgG1 Log in to see 0
1 ABIN4301539 FACS ICC IF IHC (p) IP WB Mouse IgG2a kappa Log in to see SPM587 0
1 ABIN4301540 FACS ICC IF IHC (p) IP WB Mouse IgG2a kappa Log in to see SPM587 0
1 ABIN4301541 FACS ICC IF IHC (p) IP WB Mouse IgG2a kappa Log in to see SPM587 0
1 ABIN4301564 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Alexa Fluor 488 Mouse IgG2a kappa Log in to see SPM587 0
1 ABIN4301568 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Biotin Mouse IgG2a kappa Log in to see SPM587 0
1 ABIN4301569 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB DyLight 650 Mouse IgG2a kappa Log in to see SPM587 0
1 ABIN4301573 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB DyLight 755 Mouse IgG2a kappa Log in to see SPM587 0
1 ABIN4301576 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB DyLight 550 Mouse IgG2a kappa Log in to see SPM587 0
1 ABIN4301566 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Alexa Fluor 700 Mouse IgG2a kappa Log in to see SPM587 0
1 ABIN4301571 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB DyLight 488 Mouse IgG2a kappa Log in to see SPM587 0
1 ABIN4301577 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB DyLight 350 Mouse IgG2a kappa Log in to see SPM587 0

General

Antigen Cyclin D1 (CCND1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(469), (235), (225), (44), (21), (20), (19), (17), (14), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(323), (204), (19), (5)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Cyclin D1 antibody is un-conjugated
(26), (23), (15), (10), (8), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(471), (217), (131), (122), (111), (103), (103), (79), (49), (12), (8), (8), (7), (6), (5), (3), (1), (1), (1), (1)
Pubmed 23 references available
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Product Details anti-Cyclin D1 Antibody

Target Details Cyclin D1 Application Details Handling References for anti-Cyclin D1 antibody (ABIN3043639) Images
Purpose Mouse IgG monoclonal antibody for Cyclin D1, cyclin D1 (CCND1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,mouse,rat. No cross reactivity with other proteins.
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Mouse IgG monoclonal antibody for Cyclin D1, cyclin D1 (CCND1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,mouse,rat.
Gene Name: cyclin D1
Protein Name: G1/S-specific cyclin-D1
Purification Ascites
Immunogen Recombinant human cyclin D1 protein.
Clone DCS-6
Isotype IgG2a

Target Details Cyclin D1

Product Details anti-Cyclin D1 Antibody Application Details Handling References for anti-Cyclin D1 antibody (ABIN3043639) Images back to top
Antigen
Alternative Name CCND1 (CCND1 Antibody Abstract)
Background D-type cyclins(cyclins D1, D2, and D3) are regarded as essential links between cell environment and the core cell cycle machinery. CyclinD1(CCND1), also known as BCL1. Expression of cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. CCND1 gene to 11q13. cyclin D1 gene can function as an oncogene. Cyclin D1 expression is regulated by the retinoblastoma protein.

Synonyms: BCL1|U21B31|D11S287|PRAD1|B-CELL LEUKEMIA 1|B-cell CLL/lymphoma 1|G1/S-specific cyclin D1|parathyroid adenomatosis 1|B-cell lymphoma 1 protein|BCL-1 oncogene|PRAD1 oncogene
Gene ID 595, 12443, 58919
UniProt P24385, P25322, P39948
Pathways PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling

Application Details

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Handling References for anti-Cyclin D1 antibody (ABIN3043639) Images back to top
Application Notes WB: Concentration: 4 μg/mL, Species: Human, mouse, rat
IHC-P: Concentration: 8 μg/mL, Species: Human, mouse, rat
IHC-F: Concentration: 8 μg/mL, Species: Human, mouse, rat
ICC: Concentration: 1 μg/mL, Species: Human, mouse, rat
Notes: Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921123 in WB, supported by ABIN921230 in IHC(P), IHC(F) and ICC.

Restrictions For Research Use only

Handling

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details References for anti-Cyclin D1 antibody (ABIN3043639) Images back to top
Format Lyophilized
Reconstitution Add 1 mL of PBS buffer will yield a concentration of 100 μg/mL.
Concentration 100 μg/mL
Buffer Mouse ascites fluid, 1.2 % sodium acetate, 2 mg BSA, with 0.01 mg Sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-Cyclin D1 antibody (ABIN3043639)

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling Images back to top
Product cited in:

Ren, Huang, Xu, Yang, Yang, Hu: "Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells." in: Anti-cancer drugs, Vol. 26, Issue 6, pp. 599-611, 2015

He, Chen, Wang, Zhao, Wan, Wang, Mo: "miR-204-5p promotes the adipogenic differentiation of human adipose-derived mesenchymal stem cells by modulating DVL3 expression and suppressing Wnt/?-catenin signaling." in: International journal of molecular medicine, Vol. 35, Issue 6, pp. 1587-95, 2015

Li, Gao, Chu, Teng, Lv, Yang, Yin: "The synergistic antitumor effects of all-trans retinoic acid and C-phycocyanin on the lung cancer A549 cells in vitro and in vivo." in: European journal of pharmacology, Vol. 749, pp. 107-14, 2015

Zhu, Liu, Li, Liu, Wang, Sun, Xiong, Jiang, Zheng, Hu: "Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility." in: Carcinogenesis, Vol. 35, Issue 8, pp. 1901-10, 2014

Liu, Ma, Wu, Li, Zhang, Han, Wang, Reindl, Wu, Ma: "Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-?B signaling." in: BMC cancer, Vol. 14, pp. 686, 2014

Zhang, Zhao, Huang, Meng, Bian, Li: "Melittin restores PTEN expression by down-regulating HDAC2 in human hepatocelluar carcinoma HepG2 cells." in: PLoS ONE, Vol. 9, Issue 5, pp. e95520, 2014

Liu, Zhu, Xiong, Zheng, Hu, Qiu: "Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 5750-61, 2014

Li, Zhao, Lu, Li, Yang, Wu, Liu: "Notch-1 signaling promotes the malignant features of human breast cancer through NF-?B activation." in: PLoS ONE, Vol. 9, Issue 4, pp. e95912, 2014

Liu, Yan, Li, Yin, Sun, Kou, Ye, Ferns, Liu, Liu: "Reduced expression of SOX7 in ovarian cancer: a novel tumor suppressor through the Wnt/?-catenin signaling pathway." in: Journal of ovarian research, Vol. 7, pp. 87, 2014

Cai, Wang, Zhang, Wang, Yu, Zhang, Gao, Zhang, Zhao: "Diosgenin relieves goiter via the inhibition of thyrocyte proliferation in a mouse model of Graves' disease." in: Acta pharmacologica Sinica, Vol. 35, Issue 1, pp. 65-73, 2014

Yang, Su, Lv, Xie, Liu, Cao, Sheikh, Qin, Li, Chen: "ERK1/2 mediates lung adenocarcinoma cell proliferation and autophagy induced by apelin-13." in: Acta biochimica et biophysica Sinica, Vol. 46, Issue 2, pp. 100-11, 2014

Du, Chen, Zhou, Wan, Lan, Zhang, Cao: "Estrogen induces Vav1 expression in human breast cancer cells." in: PLoS ONE, Vol. 9, Issue 6, pp. e99052, 2014

Huang, Lu, Li, Zhu, Li, Liu, Zheng, Hu: "Androglobin knockdown inhibits growth of glioma cell lines." in: International journal of clinical and experimental pathology, Vol. 7, Issue 5, pp. 2179-84, 2014

Li, Xu, Chu, Gao, Wang, Nie, Yang, Lv: "Molecular mechanism of inhibitory effects of CD59 gene on atherosclerosis in ApoE (-/-) mice." in: Immunology letters, Vol. 156, Issue 1-2, pp. 68-81, 2013

Li, Zhu, Liu, Liu, Wang, Xiong, Shen, Hu, Zheng: "ZFX knockdown inhibits growth and migration of non-small cell lung carcinoma cell line H1299." in: International journal of clinical and experimental pathology, Vol. 6, Issue 11, pp. 2460-7, 2013

Li, Tian, Wang, Yao, Zhang, Lu, Sun, Gao, Xiao, Liu: "Down-regulation of miR-129-5p inhibits growth and induces apoptosis in laryngeal squamous cell carcinoma by targeting APC." in: PLoS ONE, Vol. 8, Issue 10, pp. e77829, 2013

Zhu, Li, Xu, Liu, Tang, Xie, Xie, Liu, Wang, Gong, Hu, Zheng: "ZFX regulates glioma cell proliferation and survival in vitro and in vivo." in: Journal of neuro-oncology, Vol. 112, Issue 1, pp. 17-25, 2013

Deng, Lu, Zhao, Sun, Shi, Fan, Liu, Zhou, Nie, Wu, Fan, Guo: "Ran GTPase protein promotes human pancreatic cancer proliferation by deregulating the expression of Survivin and cell cycle proteins." in: Biochemical and biophysical research communications, Vol. 440, Issue 2, pp. 322-9, 2013

Nie, Huang, Yin, Li, Xie, Ma, Wang, Wu, Xiao: "Synergistic/additive interaction of valproic acid with bortezomib on proliferation and apoptosis of acute myeloid leukemia cells." in: Leukemia & lymphoma, Vol. 53, Issue 12, pp. 2487-95, 2012

Wu, Tao, Chen, Xu: "RhoC regulates the proliferation of gastric cancer cells through interaction with IQGAP1." in: PLoS ONE, Vol. 7, Issue 11, pp. e48917, 2012

Images

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling References for anti-Cyclin D1 antibody (ABIN3043639) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN3043639) Anti-Cyclin D1 antibody, IHC(F) IHC(F): Mouse Intestine Tissue
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN3043639) Anti-Cyclin D1 antibody, IHC(F) IHC(F): Human Placenta Tissue
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN3043639) Anti-Cyclin D1 antibody, IHC(F) IHC(F): Rat Intestine Tissue
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN3043639) Anti-Cyclin D1 antibody, IHC(F) IHC(F): Mouse Spleen Tissue