anti-Mouse (Murine) PDK2 antibody for Immunofluorescence

Recommended PDK2 Antibody (supplied by: Log in to see )

Antigen
Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) Antibodies
  • PDHK2
  • PDKII
  • Pdk
  • zgc:56209
  • PDK2
  • pyruvate dehydrogenase kinase 2
  • pyruvate dehydrogenase kinase, isoenzyme 2
  • pyruvate dehydrogenase kinase, isozyme 2b
  • PDK2
  • Pdk2
  • pdk2b
Reactivity
Human, Mouse (Murine), Rat (Rattus)
146
93
56
13
5
2
2
2
1
1
1
1
1
1
Host
Rabbit
121
42
Clonality
Polyclonal
Conjugate
This PDK2 antibody is un-conjugated
9
9
8
7
7
7
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
148
94
81
34
24
13
5
3
3
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN6259149
$ 390.77
Plus shipping costs $45.00

General

Antigen Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(146), (93), (56), (13), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(121), (42)
Clonality
Polyclonal
Conjugate This PDK2 antibody is un-conjugated
(9), (9), (8), (7), (7), (7), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(148), (94), (81), (34), (24), (13), (5), (3), (3), (2), (1), (1), (1)
Supplier Log in to see

Product Details anti-PDK2 Antibody

Target Details PDK2 Application Details Handling Images
Specificity PDK2 Antibody detects endogenous levels of total PDK2
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide
Isotype IgG
Plasmids, Primers & others

Target Details PDK2

Product Details anti-PDK2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name PDK2 (PDK2 Antibody Abstract)
Background

Description: Kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Inhibition of pyruvate dehydrogenase decreases glucose utilization and increases fat metabolism. Mediates cellular responses to insulin. Plays an important role in maintaining normal blood glucose levels and in metabolic adaptation to nutrient availability. Via its regulation of pyruvate dehydrogenase activity, plays an important role in maintaining normal blood  pH and in preventing the accumulation of ketone bodies under starvation. Plays a role in the regulation of cell proliferation and in resistance to apoptosis under oxidative stress. Plays a role in p53/TP53-mediated apoptosis.

Gene: PDK2

Molecular Weight 46 kDa
Gene ID 5164
UniProt Q15119
Pathways PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process

Application Details

Product Details anti-PDK2 Antibody Target Details PDK2 Handling Images back to top
Application Notes WB 1:500~1:1000, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-PDK2 Antibody Target Details PDK2 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

Product Details anti-PDK2 Antibody Target Details PDK2 Application Details Handling back to top
Supplier Images
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) antibody (ABIN6259149) ABIN6275430 staining HepG2 cells by IF/ICC. The sample were fixed with PFA and perme...
Western Blotting (WB) image for anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) antibody (ABIN6259149) Western blot analysis of extracts from Mouse brain, using PDK2 Antibody. Lane 1 was t...