anti-Mouse (Murine) PDK2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PDK2 Antibody (supplied by: Log in to see )

Antigen
Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) Antibodies
  • PDHK2
  • PDKII
  • Pdk
  • zgc:56209
  • PDK2
  • pyruvate dehydrogenase kinase 2
  • pyruvate dehydrogenase kinase, isoenzyme 2
  • pyruvate dehydrogenase kinase, isozyme 2b
  • PDK2
  • Pdk2
  • pdk2b
Epitope
AA 378-407, C-Term
17
13
11
10
10
7
5
5
3
3
3
2
2
2
2
2
2
1
1
1
1
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
145
91
54
12
5
2
2
2
1
1
1
1
1
1
Host
Rabbit
120
42
Clonality
Polyclonal
Conjugate
This PDK2 antibody is un-conjugated
9
9
8
7
7
7
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
147
96
81
32
22
13
6
3
3
3
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN391037
$ 385.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
15.462341 ABIN4344598 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
13 ABIN657996 IHC (p) WB Rabbit Ig Fraction AA 78-107, N-Term Log in to see Polyclonal 0
11.424261 ABIN4912898 IHC (p) WB Mouse IgG1 kappa Log in to see 180CT10-2-3 0
10 ABIN5537294 IHC (p) WB Rabbit Ig Fraction AA 78-107, N-Term Log in to see Polyclonal 0
10 ABIN3032416 ICC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
4 ABIN5961814 ELISA IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2626695 ICC IHC IHC (p) WB Rabbit IgG AA 379-392 Log in to see Polyclonal 0
1 ABIN5552188 EIA IHC (p) WB Rabbit Ig Fraction C-Term Log in to see Polyclonal 0
1 ABIN751792 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal 0
1 ABIN1811634 IHC IHC (p) WB Rabbit AA 78-107 Log in to see Polyclonal 0
1 ABIN1841117 IHC IHC (p) WB Rabbit AA 378-407 Log in to see Polyclonal 0
1 ABIN751785 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal 0
1 ABIN751783 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) Antibodies
Epitope AA 378-407, C-Term
(17), (13), (11), (10), (10), (7), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human, Monkey, Mouse (Murine), Rat (Rattus)
(145), (91), (54), (12), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(120), (42)
Clonality (Clone)
Polyclonal   ( )
Conjugate This PDK2 antibody is un-conjugated
(9), (9), (8), (7), (7), (7), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(147), (96), (81), (32), (22), (13), (6), (3), (3), (3), (1), (1), (1)
Pubmed 10 references available
Supplier Log in to see

Product Details anti-PDK2 Antibody

Target Details PDK2 Application Details Handling References for anti-PDK2 antibody (ABIN391037) Images
Specificity This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-term region of human PDK2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This PDK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-407 AA from the C-terminal region of human PDK2.
Clone RB03037
Isotype Ig Fraction
Plasmids, Primers & others

Target Details PDK2

Product Details anti-PDK2 Antibody Application Details Handling References for anti-PDK2 antibody (ABIN391037) Images back to top
Antigen
Alternative Name PDK2 (PDK2 Antibody Abstract)
Background Synonyms: Pyruvate dehydrogenase kinase isoform 2
Molecular Weight 46153 DA
Gene ID 5164
UniProt Q15119
Pathways PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process

Application Details

Product Details anti-PDK2 Antibody Target Details PDK2 Handling References for anti-PDK2 antibody (ABIN391037) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only

Handling

Product Details anti-PDK2 Antibody Target Details PDK2 Application Details References for anti-PDK2 antibody (ABIN391037) Images back to top
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-PDK2 antibody (ABIN391037)

Product Details anti-PDK2 Antibody Target Details PDK2 Application Details Handling Images back to top
Product cited in:

Hurd, Collins, Abakumova, Chouchani, Baranowski, Fearnley, Prime, Murphy, James: "Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 35153-60, 2012 Method employed by authors: Western Blotting (WB)

Love, LeBlanc, Inglis, Bradley, Choptiany, Heigenhauser, Peters: "The relationship between human skeletal muscle pyruvate dehydrogenase phosphatase activity and muscle aerobic capacity." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 111, Issue 2, pp. 427-34, 2011 Method employed by authors: Western Blotting (WB)

Dunford, Herbst, Jeoung, Gittings, Inglis, Vandenboom, LeBlanc, Harris, Peters: "PDH activation during in vitro muscle contractions in PDH kinase 2 knockout mice: effect of PDH kinase 1 compensation." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 300, Issue 6, pp. R1487-93, 2011 Method employed by authors: Western Blotting (WB)

Nicholls, Chu, Abbruzzese, Tremblay, Hardy: "Mechanism of a genetically encoded dark-to-bright reporter for caspase activity." in: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24977-86, 2011 Method employed by authors: Western Blotting (WB)

McClenaghan, Scullion, Mion, Hewage, Malthouse, Flatt, Newsholme, Brennan: "Prolonged L-alanine exposure induces changes in metabolism, Ca(2+) handling and desensitization of insulin secretion in clonal pancreatic beta-cells." in: Clinical science (London, England : 1979), Vol. 116, Issue 4, pp. 341-51, 2009 Method employed by authors: Western Blotting (WB)

Sun, Zhou, Chang, McFate, Verma, Califano: "Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 2, pp. 476-84, 2009 Method employed by authors: Western Blotting (WB)

Richards, Sardella, Schulte: "Regulation of pyruvate dehydrogenase in the common killifish, Fundulus heteroclitus, during hypoxia exposure." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 295, Issue 3, pp. R979-90, 2008 Method employed by authors: Western Blotting (WB)

Zhang, Ma, Sadana, Chowdhury, Gaillard, Wang, McDonnell, Unterman, Elam, Park: "Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression." in: The Journal of biological chemistry, Vol. 281, Issue 52, pp. 39897-906, 2006 Method employed by authors: Western Blotting (WB)

Xu, Han, Epstein, Liu: "Regulation of PDK mRNA by high fatty acid and glucose in pancreatic islets." in: Biochemical and biophysical research communications, Vol. 344, Issue 3, pp. 827-33, 2006 Method employed by authors: Western Blotting (WB)

Churchill, Murriel, Chen, Mochly-Rosen, Szweda: "Reperfusion-induced translocation of deltaPKC to cardiac mitochondria prevents pyruvate dehydrogenase reactivation." in: Circulation research, Vol. 97, Issue 1, pp. 78-85, 2005 Method employed by authors: Western Blotting (WB)

Images

Product Details anti-PDK2 Antibody Target Details PDK2 Application Details Handling References for anti-PDK2 antibody (ABIN391037) back to top
Supplier Images
Western Blotting (WB) image for anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 378-407), (C-Term) antibody (ABIN391037) Western blot analysis of PDK2 Antibody (C-term) (ABIN391037) in mouse intestine tissu...
Western Blotting (WB) image for anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 378-407), (C-Term) antibody (ABIN391037) Western blot analysis of PDK2 (arrow) using PDK2 Antibody (C-term) (ABIN391037). 293 ...
Immunohistochemistry (IHC) image for anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 378-407), (C-Term) antibody (ABIN391037) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...