EXOSC5 Protein (His tag)
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- Target See all EXOSC5 Proteins
- EXOSC5 (Exosome Component 5 (EXOSC5))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This EXOSC5 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product EXOSC5 Protein
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- Comment
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Synonyms: Exosome complex component RRP46, hRrp46p, p12B, RRP41B, RRP46, Rrp46p
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- PBS (pH 7.4) containing 2 mM DTT, 30% glycerol, 200 mM NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- EXOSC5 (Exosome Component 5 (EXOSC5))
- Alternative Name
- EXOSC5 (EXOSC5 Products)
- Synonyms
- si:ch211-194n6.2 Protein, zgc:153707 Protein, EXOSC5 Protein, RRP41B Protein, RRP46 Protein, Rrp46p Protein, hRrp46p Protein, p12B Protein, D7Wsu180e Protein, exosome component 5 Protein, exosc5 Protein, EXOSC5 Protein, Exosc5 Protein
- Background
- EXOSC5, also known as exosome component 5, belongs to the RNase PH family. EXOSC5 has been shown to interact with Exosome component 8 and Exosome component 1. It is Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. It highly expressed in a variety of hematopoietic and epithelial tumor cell lines, but not in normal hematopoietic tissues or other normal tissue, with the exception of testis. Recombinant human EXOSC5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 27.5kDa (256aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_064543
- Pathways
- SARS-CoV-2 Protein Interactome
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