SMUG1 Protein (His tag)
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- Target See all SMUG1 Proteins
- SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SMUG1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product SMUG1 Protein
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- Comment
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Synonyms: Single-strand-selective monofunctional uracil-DNA glycosylase, FDG, HMUDG, UNG3
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 30% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
- Alternative Name
- SMUG1 (SMUG1 Products)
- Synonyms
- SMUG1 Protein, xsmug1 Protein, 1200013B09Rik Protein, A930006H09Rik Protein, C85220 Protein, FDG Protein, HMUDG Protein, UNG3 Protein, single-strand-selective monofunctional uracil-DNA glycosylase 1 Protein, single-strand selective monofunctional uracil DNA glycosylase Protein, single-strand-selective monofunctional uracil-DNA glycosylase 1 L homeolog Protein, SMUG1 Protein, smug1 Protein, smuG1 Protein, smuG Protein, LOC5577584 Protein, CpipJ_CPIJ002767 Protein, Smug1 Protein, smug1.L Protein
- Background
- Single-strand-selective monofunctional uracil-DNA glycosylase, also known as SMUG1, is a enzyme responsible for recognizing base lesions in the genome and initiating base excision DNA repair. This protein acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA and has a preference for single-stranded DNA substrates. Recombinant human SMUG1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 32.3 kDa (293aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_055126
- Pathways
- DNA Damage Repair
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