POFUT1 Protein (His tag)
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- Target See all POFUT1 Proteins
- POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This POFUT1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product POFUT1 Protein
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- Comment
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Synonyms: GDP-fucose protein O-fucosyltransferase 1, FUT12, O-Fuc-T, O-FucT-1, O-FUT
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))
- Alternative Name
- POFUT1 (POFUT1 Products)
- Synonyms
- fut12 Protein, zgc:110472 Protein, o-fut Protein, o-fuc-t Protein, o-fuct-1 Protein, pofut1 Protein, DDD2 Protein, FUT12 Protein, O-FUT Protein, O-Fuc-T Protein, O-FucT-1 Protein, OFUCT1 Protein, mKIAA0180 Protein, Fut12 Protein, protein O-fucosyltransferase 1 Protein, POFUT1 Protein, pofut1 Protein, Pofut1 Protein
- Background
- GDP-fucose protein O-fucosyltransferase 1, also known as POUFUT1, is a member of the glycosyltransferase O-Fuc family. Highly expressed in pancreas, kidney, lung, heart, brain, liver, placenta and skeletal muscle, POFUT1 uses manganese to catalyze the attachment of fucose to a conserved serine or threonine residue on a protein accept. POFUT1 plays an important role in Notch signaling, as Notch ligands can serve as POFUT1 substrates. Recombinant human POFUT1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 43.7kDa (385aa)
- NCBI Accession
- NP_056167
- Pathways
- Notch Signaling, SARS-CoV-2 Protein Interactome
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