XPA Protein (His tag)
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- Target See all XPA Proteins
- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This XPA protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product XPA Protein
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- Comment
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Synonyms: DNA repair protein complementing XP-A cells, XP1, XPAC
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
- Alternative Name
- XPA (XPA Products)
- Synonyms
- CG6358 Protein, DhR14 Protein, DhXPA Protein, DmXPA Protein, Dmel\\CG6358 Protein, Dxpa Protein, EG:EG0007.8 Protein, XPAC Protein, XPA_DROME Protein, Xpa Protein, dmXPA Protein, dxpa Protein, XP1 Protein, AI573865 Protein, Xpac Protein, xpac Protein, xxpa Protein, Xeroderma pigmentosum group A-like Protein, XPA, DNA damage recognition and repair factor Protein, xeroderma pigmentosum, complementation group A Protein, xeroderma pigmentosum, complementation group A L homeolog Protein, Xpac Protein, XPA Protein, Xpa Protein, xpa.L Protein
- Background
- XPA, also known as DNA repair protein complementing XP-A cells, belong to the XPA family. This protein is involved in DNA excision repair. It Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Defects in XPA are a cause of xeroderma pigmentosum complementation group A (XP-A), which is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities. Recombinant human XPA protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 33.8 kDa (296aa)
- NCBI Accession
- NP_000371
- Pathways
- DNA Damage Repair
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