FAS Protein (AA 26-170) (Fc Tag)
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- Target See all FAS Proteins
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 26-170
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Origin
- Human, Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FAS protein is labelled with Fc Tag.
- Application
- SDS-PAGE (SDS)
- Specificity
- Binds human and mouse FasL.
- Cross-Reactivity
- Human, Mouse (Murine)
- Characteristics
- The Fc portion of human IgG1 is fused to the C-terminus of human Fas (aa 26-170).
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FAS Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Blocks the binding of FasL to Fas.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 50 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- Alternative Name
- Fas (FAS Products)
- Synonyms
- ALPS1A Protein, APO-1 Protein, APT1 Protein, CD95 Protein, FAS1 Protein, FASTM Protein, TNFRSF6 Protein, AI196731 Protein, APO1 Protein, TNFR6 Protein, Tnfrsf6 Protein, lpr Protein, Fas cell surface death receptor Protein, Fas (TNF receptor superfamily member 6) Protein, FAS Protein, Fas Protein, fas Protein
- Background
- FasL is a cytokine that binds to Fas/TNFRSF6, a receptor that transduces the apoptotic signal into cells. FasL is involved in cytotoxic T cell mediated apoptosis and in T cell development.
- Molecular Weight
- ~47kDa (SDS-PAGE)
- UniProt
- P25445
- Pathways
- p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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