SHP1 Protein (AA 1-373) (His tag)

Catalog No. ABIN1609810

Product Details

Target: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Protein Type: Recombinant

Protein Characteristics: AA 1-373

Origin: Emericella nidulans

Source: Yeast

Purification tag / Conjugate: This SHP1 protein is labelled with His tag.

Application: ELISA

Sequence: MNPAEHDEAV SQFCAMTRAR PDEAQEYLAT NGWDLEAAVT EFFAEQDETA GSSEPTGQPS
AKSSSSTPRE SSSSRKQPPK KFATLGDLAS GAADSSDDDD DENQDFFAGG EKSGLAVQNP
DDLKKKIIEK ARRTQLPASD DSEPRRNYFT GPARTLGGED TPSRVIDTPS GPAQPQIPRR
VRRTLHFWAD GFSVDDGELY RSDDPQNAEI LNSIRQGRAP LSIMNAQHGQ DVDVEIKQHD
EKYVRPKPKY QPFAGKGQRL GSPTPGIRAP APSEPAPAPQ SSSGPPKPNV DESQPVVTLQ
IRLGDGTRLT SRFNTTHTIG DVYDFVSAAS PQSQARPWVL LTTFPSKELT DKAAVLGDLP
EFKRGGVVVQ KWQ

Specificity: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Alternative Name: UBX domain-containing protein 1 (ubx1) (PTPN6 Products)

Synonyms: HCPH Protein, HPTP1C Protein, PTP-1C Protein, SH-PTP1 Protein, SHP-1 Protein, SHP-1L Protein, SHP1 Protein, DRPLA Protein, Hcph Protein, Ptp1C Protein, me Protein, motheaten Protein, Ptph6 Protein, Shp-1 Protein, fj22f05 Protein, wu:fj22f05 Protein, zgc:55501 Protein, ptpn6 Protein, protein tyrosine phosphatase, non-receptor type 6 Protein, protein tyrosine phosphatase, non-receptor type 6 L homeolog Protein, PTPN6 Protein, Ptpn6 Protein, ptpn6 Protein, ptpn6.L Protein

Background: Recommended name: UBX domain-containing protein 1

UniProt: P0C8Q0

Pathways: JAK-STAT Signaling, TCR Signaling, TLR Signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling