RAF1 Protein (AA 2061-2302) (GST tag)
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- Target See all RAF1 Proteins
- RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2061-2302
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Origin
- Hepatitis C Virus (HCV)
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RAF1 protein is labelled with GST tag.
- Application
- ELISA, Western Blotting (WB)
- Characteristics
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Purified recombinant Hepatitis C Virus NS5 protein
Expression System: E.coli - Purification
- Proprietary chromatographic technique
- Purity
- > 95 % pure
- Top Product
- Discover our top product RAF1 Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 25 mM tris-HCl, pH -8, with 1.5 M urea, 0.2 % Triton-X and 52 % glycerol.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
- Alternative Name
- NS5 (RAF1 Products)
- Synonyms
- CRAF Protein, NS5 Protein, Raf-1 Protein, c-Raf Protein, c-raf Protein, craf Protein, raf1 Protein, RAF1 Protein, 6430402F14Rik Protein, AA990557 Protein, BB129353 Protein, Craf1 Protein, D830050J10Rik Protein, v-Raf Protein, raf Protein, cRaf Protein, Raf-1 proto-oncogene, serine/threonine kinase Protein, Raf-1 proto-oncogene, serine/threonine kinase a Protein, v-raf-leukemia viral oncogene 1 Protein, Raf-1 proto-oncogene, serine/threonine kinase S homeolog Protein, RAF1 Protein, Raf1 Protein, raf1a Protein, raf1 Protein, raf1.S Protein
- Background
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HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Alternative Names: HCV Recombinant protein, Hep C protein, Hepatitis C protein, HCV NS5 protein, HCV protein - Pathways
- MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Stem Cell Maintenance, Hepatitis C, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling, BCR Signaling
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