IL27 Receptor alpha Protein (AA 33-514) (Fc Tag)
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- Target See all IL27 Receptor alpha (IL27RA) Proteins
- IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 33-514
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL27 Receptor alpha protein is labelled with Fc Tag.
- Sequence
- AA 33-514
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 79 kDa. The protein migrates as 105-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL27RA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))
- Alternative Name
- IL-27 Ra (IL27RA Products)
- Synonyms
- IL27RA Protein, CRL1 Protein, IL-27RA Protein, IL27R Protein, TCCR Protein, WSX1 Protein, zcytor1 Protein, IL-27R Protein, Tccr Protein, WSX-1 Protein, Wsx1 Protein, interleukin 27 receptor subunit alpha Protein, interleukin-27 receptor subunit alpha Protein, interleukin 27 receptor, alpha Protein, IL27RA Protein, LOC484907 Protein, Il27ra Protein
- Background
- Interleukin-27 receptor subunit alpha ( IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily. IL27RA contains three fibronectin type-III domains. IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27. IL27RA involved in the regulation of Th1-type immune responses. IL27RA also appears to be involved in innate defense mechanisms.
- Molecular Weight
- 78.9 kDa
- Pathways
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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