JAG1 Protein (AA 34-1046) (His tag)
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- Target See all JAG1 Proteins
- JAG1 (Jagged 1 (JAG1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 34-1046
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This JAG1 protein is labelled with His tag.
- Sequence
- AA 34-1046
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 112.3 kDa. The protein migrates as 160-180 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >90 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product JAG1 Protein
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Jagged 1 (JAG1) (AA 531-620) protein (GST tag)
JAG1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Jagged 1 (JAG1) (AA 37-119) protein (GST tag)JAG1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Jagged 1 (JAG1) (AA 1-1067), (Extracellular Domain) (Active) protein (Fc Tag)JAG1 Origin: Human Host: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -70 °C.
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- Target
- JAG1 (Jagged 1 (JAG1))
- Alternative Name
- Jagged 1 (JAG1 Products)
- Synonyms
- AGS Protein, AHD Protein, AWS Protein, CD339 Protein, HJ1 Protein, JAGL1 Protein, ABE2 Protein, Gsfabe2 Protein, Htu Protein, Ozz Protein, Ser-1 Protein, JAG1 Protein, jag3 Protein, cb243 Protein, jag1 Protein, sb:cb243 Protein, serrateC Protein, jagged1 Protein, serrate Protein, serrate-1 Protein, x-serrate-1 Protein, jagged 1 Protein, jagged 1b Protein, jagged 1a Protein, jagged 1 L homeolog Protein, JAG1 Protein, Jag1 Protein, jag1 Protein, jag1b Protein, jag1a Protein, jag1.L Protein
- Background
- Protein jagged-1 (JAG1) is also known as Jagged1, hJ1, JAGL1 and CD339, which is a single-pass type I membrane protein containing one DSL domain and 15 EGF-like domains. JAG1 is widely expressed in adult and fetal tissues,the expression of JAG1 is up-regulated in cervical squamous cell carcinoma and also expressed in bone marrow cell line HS-27a.JAG1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. JAG1 is involved in early and late stages of mammalian cardiovascular development. JAG1 inhibits myoblast differentiation by similarity and enhances fibroblast growth factor-induced angiogenesis (in vitro).
- Molecular Weight
- 112.3 kDa
- NCBI Accession
- NP_000205
- Pathways
- Notch Signaling, Stem Cell Maintenance
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