PROCR Protein (AA 18-209) (Fc Tag)
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- Target See all PROCR Proteins
- PROCR (Protein C Receptor, Endothelial (PROCR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 18-209
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PROCR protein is labelled with Fc Tag.
- Sequence
- AA 18-209
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.6 kDa. As a result of glycosylation, the protein migrates as 65 kDa under reducing (R) condition, and 125 kDa under non-reducing (NR) condition (SDS-PAGE).
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product PROCR Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- PROCR (Protein C Receptor, Endothelial (PROCR))
- Alternative Name
- PROCR (PROCR Products)
- Synonyms
- PROCR Protein, CCCA Protein, CCD41 Protein, EPCR Protein, AI325044 Protein, Ccca Protein, Ccd41 Protein, Epcr Protein, protein C receptor Protein, protein C receptor, endothelial Protein, PROCR Protein, Procr Protein
- Background
- Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201. PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists. PROCR is probably released by a metalloprotease. PROCR seems to have the same activity as the membrane-bound form. PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung. PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex. PROCR plays a role in the protein C pathway controlling blood coagulation.
- Molecular Weight
- 48.6 kDa
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