NPPB Protein
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- Target See all NPPB Proteins
- NPPB (Natriuretic Peptides B (NPPB))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Natriuretic peptides B protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- < 0.1 EU per μg protein as determined by LAL test
- Top Product
- Discover our top product NPPB Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 20 mM Phosphate buffer, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, 20 % Glycerol, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NPPB (Natriuretic Peptides B (NPPB))
- Alternative Name
- Natriuretic Peptides B (NPPB Products)
- Synonyms
- BNP1 Protein, NPPB Protein, BNP Protein, Bnf Protein, AA408272 Protein, natriuretic peptide B Protein, natriuretic peptide type B Protein, NPPB Protein, Nppb Protein
- Background
- This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein&aposs biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
- Molecular Weight
- 14.2 kDa
- NCBI Accession
- NP_002512
- Pathways
- Hormone Activity
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