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NPPB Protein

NPPB Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2726862
  • Target See all NPPB Proteins
    NPPB (Natriuretic Peptides B (NPPB))
    Protein Type
    Recombinant
    Origin
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 6
    • 1
    Escherichia coli (E. coli)
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Natriuretic peptides B protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    < 0.1 EU per μg protein as determined by LAL test
    Top Product
    Discover our top product NPPB Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    20 mM Phosphate buffer, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, 20 % Glycerol, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    NPPB (Natriuretic Peptides B (NPPB))
    Alternative Name
    Natriuretic Peptides B (NPPB Products)
    Synonyms
    BNP1 Protein, NPPB Protein, BNP Protein, Bnf Protein, AA408272 Protein, natriuretic peptide B Protein, natriuretic peptide type B Protein, NPPB Protein, Nppb Protein
    Background
    This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein&aposs biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
    Molecular Weight
    14.2 kDa
    NCBI Accession
    NP_002512
    Pathways
    Hormone Activity
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