NFAT1 Protein (Transcript Variant D) (Myc-DYKDDDDK Tag)
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- Target See all NFAT1 Proteins
- NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant D
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NFAT1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NFATC2 (transcript variant D) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NFAT1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
- Alternative Name
- Nfatc2 (NFAT1 Products)
- Synonyms
- NFATC2 Protein, AI607462 Protein, NF-ATc2 Protein, NFAT1 Protein, NFAT1-D Protein, Nfatp Protein, NFATP Protein, nuclear factor of activated T-cells 2 Protein, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 Protein, NFATC2 Protein, nfatc2 Protein, Nfatc2 Protein
- Background
- This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.
- Molecular Weight
- 97.5 kDa
- NCBI Accession
- NP_001129493
- Pathways
- RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling, BCR Signaling
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