TLE3 Protein (DYKDDDDK Tag)

Catalog No. ABIN2733814

Product Details

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Protein Type: Recombinant

Origin: Human

Source: Insect cells (Sf9)

Purification tag / Conjugate: This TLE3 protein is labelled with DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human TLE3 (full length, C-term DDK tag, transcript variant 1) protein expressed in Sf9 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Alternative Name: Tle3 (TLE3 Products)

Synonyms: TLE3 Protein, ESG Protein, ESG1 Protein, Xesg1 Protein, esg2 Protein, esg3 Protein, grg2 Protein, grg3 Protein, hst18976 Protein, tle3 Protein, xgrg3 Protein, ESG3 Protein, GRG3 Protein, HsT18976 Protein, Esp3 Protein, 2610103N05Rik Protein, Grg3a Protein, Grg3b Protein, mKIAA1547 Protein, transducin like enhancer of split 3 Protein, transducin like enhancer of split 2 Protein, transducin-like enhancer of split 3 Protein, TLE3 Protein, tle2 Protein, Tle3 Protein

Background: This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Molecular Weight: 83.4 kDa

NCBI Accession: NP_005069

Pathways: SARS-CoV-2 Protein Interactome