JAK1 Protein (Myc-DYKDDDDK Tag)
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- Target See all JAK1 Proteins
- JAK1 (Janus Kinase 1 (JAK1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This JAK1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Tyrosine-protein kinase JAK1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product JAK1 Protein
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Janus Kinase 1 (JAK1) (AA 850-1154) (Active) protein (GST tag)
JAK1 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
Janus Kinase 1 (JAK1) (AA 221-320) protein (GST tag)JAK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Janus Kinase 1 (JAK1) (AA 1-1154) protein (Strep Tag)Crystallography grade JAK1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Janus Kinase 1 (JAK1) (AA 1-1153) protein (Strep Tag)Crystallography grade JAK1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Janus Kinase 1 (JAK1) (AA 561-852) protein (His tag)JAK1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS-PAGE.
Janus Kinase 1 (JAK1) proteinJAK1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- JAK1 (Janus Kinase 1 (JAK1))
- Alternative Name
- Tyrosine-Protein Kinase Jak1 (JAK1 Products)
- Synonyms
- JAK1A Protein, JAK1B Protein, JTK3 Protein, AA960307 Protein, C130039L05Rik Protein, wu:fb93e10 Protein, jak1 Protein, Janus kinase 1 Protein, tyrosine-protein kinase JAK1 Protein, JAK1 Protein, Jak1 Protein, jak1 Protein, LOC100286690 Protein
- Background
- This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 133.1 kDa
- NCBI Accession
- NP_002218
- Pathways
- JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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