JAK1 Protein (AA 561-852) (His tag)
-
- Target See all JAK1 Proteins
- JAK1 (Janus Kinase 1 (JAK1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 561-852
-
Origin
- Human
-
Source
- Insect Cells
- Purification tag / Conjugate
- This JAK1 protein is labelled with His tag.
- Characteristics
- Human JAK1 Protein, His Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product JAK1 Protein
-
Janus Kinase 1 (JAK1) (AA 850-1154) (Active) protein (GST tag)
JAK1 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
Janus Kinase 1 (JAK1) (AA 221-320) protein (GST tag)JAK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Janus Kinase 1 (JAK1) (AA 1-1154) protein (Strep Tag)Crystallography grade JAK1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Janus Kinase 1 (JAK1) (AA 1-1153) protein (Strep Tag)Crystallography grade JAK1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Janus Kinase 1 (JAK1) proteinJAK1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Janus Kinase 1 (JAK1) protein (Myc-DYKDDDDK Tag)JAK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- 50 mM Tris, 500 mM NaCl, 2 mM TCEP, pH 8.0
- Storage
- -80 °C
-
- Target
- JAK1 (Janus Kinase 1 (JAK1))
- Alternative Name
- JAK1 (JAK1 Products)
- Synonyms
- JAK1A Protein, JAK1B Protein, JTK3 Protein, AA960307 Protein, C130039L05Rik Protein, wu:fb93e10 Protein, jak1 Protein, Janus kinase 1 Protein, tyrosine-protein kinase JAK1 Protein, JAK1 Protein, Jak1 Protein, jak1 Protein, LOC100286690 Protein
- Background
- JAK1 is a human tyrosine kinase protein essential for signaling for certain type I and type II cytokines. It interacts with the common gamma chain (γc) of type I cytokine receptors, to elicit signals from the IL-2 receptor family (e.g. IL-2R, IL-7R, IL-9R and IL-15R), the IL-4 receptor family (e.g. IL-4R and IL-13R), the gp130 receptor family (e.g. IL-6R, IL-11R, LIF-R, OSM-R, cardiotrophin-1 receptor (CT-1R), ciliary neurotrophic factor receptor (CNTF-R), neurotrophin-1 receptor (NNT-1R) and Leptin-R). Jak1 plays a critical role in initiating responses to multiple major cytokine receptor families. Expression of JAK1 in cancer cells enables individual cells to contract, potentially allowing them to escape their tumor and metastasize to other parts of the body
- Molecular Weight
- 35.7 kDa
- Pathways
- JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
-
