SOD2 Protein (AA 1-222) (His tag)
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- Target See all SOD2 Proteins
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-222
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SOD2 protein is labelled with His tag.
- Purpose
- Recombinant Human SOD2/Mn-SOD (N-6His)
- Sequence
- MHHHHHHDDD DKKHSLPDLP YDYGALEPHI NAQIMQLHHS KHHAAYVNNL NVTEEKYQEA LAKGDVTAQI ALQPALKFNG GGHINHSIFW TNLSPNGGGE PKGELLEAIK RDFGSFDKFK EKLTAASVGV QGSGWGWLGF NKERGHLQIA ACPNQDPLQG TTGLIPLLGI DVWEHAYYLQ YKNVRPDYLK AIWNVINWEN VTERYMACKK
- Characteristics
- Recombinant Human Superoxide Dismutase [Mn] Mitochondrial/SOD2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Lys222) of Human SOD2 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SOD2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,100 mM NaCl,50 % glycerol, pH 8.0.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
- Alternative Name
- SOD2 (SOD2 Products)
- Synonyms
- LOC100101896 Protein, MNSOD Protein, GB14346 Protein, sod2 Protein, MGC88869 Protein, Sod2 Protein, CG8905 Protein, Dmel\\CG8905 Protein, Mito SOD Protein, Mn SOD Protein, Mn-SOD Protein, Mn-SOD2 Protein, MnSOD Protein, MnSODII Protein, Mn[2+]SOD Protein, SOD Protein, SOD-2 Protein, SOD2 Protein, Sod-2 Protein, dSOD2 Protein, mitSOD2 Protein, mnSOD Protein, IPOB Protein, MVCD6 Protein, cb463 Protein, wu:fj33b01 Protein, zgc:73051 Protein, MnSOD Protein, manganese superoxide dismutase Protein, superoxide dismutase 2, mitochondrial Protein, superoxide dismutase 2 Protein, Mn superoxide dismutase Protein, Superoxide dismutase 2 (Mn) Protein, superoxide dismutase 2 L homeolog Protein, BDBG_07234 Protein, LOC100101896 Protein, MNSOD Protein, Sod2 Protein, sod2 Protein, LbMnSOD4 Protein, SOD2 Protein, LOC100282741 Protein, SOD-2 Protein, sod2.L Protein
- Sub Type
- Fusionprotein
- Background
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Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. The SOD2 protein transforms toxic superoxide and a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. Genetic variation in SOD2 is associated with microvascular complications of diabetes type 6 (MVCD6), idiopathic cardiomyopathy (IDC), sporadic motor neuron disease, and cancer. SOD2 destroys superoxide anion radicals which are usually produced within the cells and which are toxic to biological systems.
Alternative Names: Superoxide Dismutase [Mn] Mitochondrial, SOD2 - Molecular Weight
- 23.7 kDa
- UniProt
- P04179
- Pathways
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling
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