Epiregulin Protein (EREG)
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- Target See all Epiregulin (EREG) Proteins
- Epiregulin (EREG)
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func)
- Sequence
- VAQVSITKCS SDMNGYCLHG QCIYLVDMSQ NYCRCEVGYT GVRCEHFFL
- Characteristics
- Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 2 ng/mL, corresponding to a specific activity of > 5.0 x 105 IU/mg.
- Purity
- >97 % as determined by SDS-PAGE and HPLC.
- Sterility
- 0.2 μm filtered
- Top Product
- Discover our top product EREG Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- Epiregulin (EREG)
- Alternative Name
- EREG (EREG Products)
- Synonyms
- EREG Protein, ER Protein, EPR Protein, proepiregulin Protein, epiregulin Protein, EREG Protein, ereg Protein, Ereg Protein
- Background
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Relevance: Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis. {ECO:0000269|PubMed:9419975}.
Synonyms: EPR, - Molecular Weight
- 5.6 kDa
- UniProt
- O14944
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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