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Epiregulin Protein (EREG)

EREG Origin: Human Host: Escherichia coli (E. coli) Recombinant >97 % as determined by SDS-PAGE and HPLC. Func Active
Catalog No. ABIN2830606
  • Target See all Epiregulin (EREG) Proteins
    Epiregulin (EREG)
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 11
    • 4
    • 1
    Human
    Source
    • 7
    • 4
    • 2
    • 2
    Escherichia coli (E. coli)
    Application
    Functional Studies (Func)
    Sequence
    VAQVSITKCS SDMNGYCLHG QCIYLVDMSQ NYCRCEVGYT GVRCEHFFL
    Characteristics
    Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 2 ng/mL, corresponding to a specific activity of > 5.0 x 105 IU/mg.
    Purity
    >97 % as determined by SDS-PAGE and HPLC.
    Sterility
    0.2 μm filtered
    Top Product
    Discover our top product EREG Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
  • Target
    Epiregulin (EREG)
    Alternative Name
    EREG (EREG Products)
    Synonyms
    EREG Protein, ER Protein, EPR Protein, proepiregulin Protein, epiregulin Protein, EREG Protein, ereg Protein, Ereg Protein
    Background
    Relevance: Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis. {ECO:0000269|PubMed:9419975}.
    Synonyms: EPR,
    Molecular Weight
    5.6 kDa
    UniProt
    O14944
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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