TNFRSF18 Protein (AA 20-121) (His tag)
-
- Target See all TNFRSF18 Proteins
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-121
-
Origin
- Rat
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TNFRSF18 protein is labelled with His tag.
- Application
- Functional Studies (Func)
- Sequence
- AA 20-121
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.1 kDa. The protein migrates as 21 kDa under reducing (R) condition (SDS-PAGE).
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product TNFRSF18 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
-
- Target
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- Alternative Name
- GITR (TNFRSF18 Products)
- Synonyms
- GITR Protein, TNFRSF18 Protein, AITR Protein, Gitr Protein, CD357 Protein, GITR-D Protein, TNF receptor superfamily member 18 Protein, tumor necrosis factor receptor superfamily, member 18 Protein, TNFRSF18 Protein, Tnfrsf18 Protein
- Background
- Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
- Molecular Weight
- 12.3 kDa
- UniProt
- Q5M835
- Pathways
- Cancer Immune Checkpoints
-