MEK1 Protein (Pro124Leu-Mutant) (GST tag)

Catalog No. ABIN5569647

Product Details

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Protein Type: Recombinant

Biological Activity: Active

Protein Characteristics: Pro124Leu-Mutant

Origin: Human

Source: Insect cells (Sf21)

Purification tag / Conjugate: This MEK1 protein is labelled with GST tag.

Application: SDS-PAGE (SDS), Functional Studies (Func)

Purpose: MAP2K1 (P124L) (Human) Recombinant Protein

Characteristics: Human MAP2K1 (NP_002746.1, 1 a.a. - 393 a.a.) P124L mutant full length protein with GST tag co-expressed with His-tagged RAF1 (NP_002871.1, 306 a.a. - 648 a.a.) Y340D/Y341D mutant full length recombinant protein in Baculovirus infected Sf21 cells.
This product with activity data is belong to bioactive protein.

Purification: Baculovirus infected insect cell (Sf21) expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Baculovirus infected insect cell (Sf21) expression system
Product Quality tested by: SDS-PAGE Stained with Coomassie Blue

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05 % Brij35, 1 mM DTT, 10 % glycerol)

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Target Details

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Alternative Name: MAP2K1 (MAP2K1 Products)

Synonyms: Mek1 Protein, CFC3 Protein, MAPKK1 Protein, MEK1 Protein, MKK1 Protein, PRKMK1 Protein, MEKK1 Protein, Prkmk1 Protein, mek-2 Protein, si:ch211-242m18.2 Protein, wu:fj56a12 Protein, wu:fj61b01 Protein, zgc:56557 Protein, ATMEK1 Protein, F20B18.180 Protein, F20B18_180 Protein, MAP kinase/ ERK kinase 1 Protein, MITOGEN ACTIVATED PROTEIN KINASE KINASE Protein, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 Protein, NMAPKK Protein, MEK Protein, mitogen activated protein kinase kinase 1 Protein, mitogen-activated protein kinase kinase 1 Protein, mitogen-activated protein kinase kinase 1 L homeolog Protein, MAP kinase/ ERK kinase 1 Protein, Map2k1 Protein, MAP2K1 Protein, map2k1.L Protein, map2k1 Protein, MEK1 Protein

Background: Full Gene Name: mitogen-activated protein kinase kinase 1
Synonyms: MAPKK1,MEK1,MKK1,PRKMK1

Gene ID: 5604

Pathways: MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling