CD58 Protein (CD58) (partial) (Fc Tag)
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- Target See all CD58 Proteins
- CD58
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- partial
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD58 protein is labelled with Fc Tag.
- Application
- Western Blotting (WB), ELISA
- Sequence
- Phe 29 - Arg 215
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
- Biological Activity Comment
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Measured by its binding ability in a functional ELISA. Immobilized Human CD2, His Tag at 2 μg/mL (100 uL/well) can bind Human CD58, Fc Tag with a linear range of 10-156 ng/mL (QC tested).
- Top Product
- Discover our top product CD58 Protein
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- Application Notes
- This recombinant protein can be used for E, WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Target
- CD58
- Alternative Name
- CD58 (CD58 Products)
- Synonyms
- LFA-3 Protein, LFA3 Protein, ag3 Protein, CD58 molecule Protein, CD58 Protein
- Background
- CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.
- Molecular Weight
- 48.1 kDa
- Gene ID
- 965
- UniProt
- Q9BRW0
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