IL22 Receptor alpha 1 Protein (AA 250-573, Cytosolic, partial) (His-SUMO Tag)
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- Target See all IL22 Receptor alpha 1 (IL22RA1) Proteins
- IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))
- Protein Type
- Recombinant
- Protein Characteristics
- Cytosolic, AA 250-573, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IL22 Receptor alpha 1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- SYRYVTKPPA PPNSLNVQRV LTFQPLRFIQ EHVLIPVFDL SGPSSLAQPV QYSQIRVSGP REPAGAPQRH SLSEITYLGQ PDISILQPSN VPPPQILSPL SYAPNAAPEV GPPSYAPQVT PEAQFPFYAP QAISKVQPSS YAPQATPDSW PPSYGVCMEG SGKDSPTGTL SSPKHLRPKG QLQKEPPAGS CMLGGLSLQE VTSLAMEESQ EAKSLHQPLG ICTDRTSDPN VLHSGEEGTP QYLKGQLPLL SSVQIEGHPM SLPLQPPSRP CSPSDQGPSP WGLLESLVCP KDEAKSPAPE TSDLEQPTEL DSLFRGLALT VQWE
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product IL22RA1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))
- Alternative Name
- I22R1 (IL22RA1 Products)
- Synonyms
- IL22RA1 Protein, CRF2-9 Protein, IL22R Protein, IL22R1 Protein, 9130219A07Rik Protein, ENSMUSG00000073746 Protein, IL-22R Protein, Il22r Protein, RGD1559655 Protein, interleukin 22 receptor subunit alpha 1 Protein, interleukin 22 receptor, alpha 1 Protein, IL22RA1 Protein, Il22ra1 Protein
- Background
- Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
- Molecular Weight
- 50.8 kDa
- UniProt
- Q8N6P7
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