Caspase 3 Protein (CASP3) (AA 29-175, partial) (His tag)
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- Target See all Caspase 3 (CASP3) Proteins
- Caspase 3 (CASP3)
- Protein Type
- Recombinant
- Protein Characteristics
- partial, AA 29-175
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Caspase 3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- SGISLDNSYK MDYPEMGLCI IINNKNFHKS TGMTSRSGTD VDAANLRETF RNLKYEVRNK NDLTREEIVE LMRDVSKEDH SKRSSFVCVL LSHGEEGIIF GTNGPVDLKK ITNFFRGDRC RSLTGKPKLF IIQACRGTEL DCGIETD
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product CASP3 Protein
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Caspase 3 (CASP3) (AA 29-277) protein (His-IF2DI Tag)
CASP3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Caspase 3 (CASP3) (AA 1-277) protein (GST tag)CASP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Caspase 3 (CASP3) (AA 1-100) protein (GST tag)CASP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Caspase 3 (CASP3) (AA 176-277) protein (GST tag)CASP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Caspase 3 (CASP3)
- Alternative Name
- CASP3 (CASP3 Products)
- Synonyms
- CPP32 Protein, CPP32B Protein, SCA-1 Protein, A830040C14Rik Protein, AC-3 Protein, Apopain Protein, CC3 Protein, Caspase-3 Protein, Lice Protein, Yama Protein, mldy Protein, xcpp32 Protein, casp3 Protein, zgc:100890 Protein, CASP-3 Protein, caspase-3 Protein, caspase 3 Protein, caspase 3 S homeolog Protein, caspase 3, apoptosis-related cysteine peptidase a Protein, caspase 3, apoptosis-related cysteine peptidase Protein, CASP3 Protein, Casp3 Protein, casp3.S Protein, casp3a Protein
- Background
- Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory elent binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the mbrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
- Molecular Weight
- 20.7 kDa
- UniProt
- P42574
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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