NADPH Oxidase 4 Protein (NOX4) (AA 210-424, Extracellular) (His-SUMO Tag)
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- Target See all NADPH Oxidase 4 (NOX4) Proteins
- NADPH Oxidase 4 (NOX4)
- Protein Type
- Recombinant
- Protein Characteristics
- Extracellular, AA 210-424
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Origin
- Rat
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Source
- Yeast
- Purification tag / Conjugate
- This NADPH Oxidase 4 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- GGLLKYQTNL DTHPPGCISL NRTPSQNMSI ADYVSEHFHG SLPGGFSKLE DHYQKTLVKI CLEEPKFQAH FPQTWIWISG PLCLYCAERL YRCIRSNKPV TIISVINHPS DVMELRMIKE NFKARPGQYI ILHCPSVSAL ENHPFTLTMC PTETKATFGV HFKVVGDWTE RFRDLLLPPS SQDSEILPFI QSRNYPKLYI DGPFGSPFEE SLNYE
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product NOX4 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- NADPH Oxidase 4 (NOX4)
- Alternative Name
- NOX4 (NOX4 Products)
- Synonyms
- KOX Protein, KOX-1 Protein, RENOX Protein, AI648021 Protein, nox4 Protein, NOX4 Protein, NADPH oxidase 4 Protein, NOX4 Protein, Nox4 Protein, nox4 Protein, PTRG_09562 Protein
- Background
- Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
- Molecular Weight
- 40.6 kDa
- UniProt
- Q924V1
- Pathways
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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