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NADPH Oxidase 4 Protein (NOX4) (AA 210-424, Extracellular) (His-SUMO Tag)

NOX4 Origin: Rat Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN5713704
  • Target See all NADPH Oxidase 4 (NOX4) Proteins
    NADPH Oxidase 4 (NOX4)
    Protein Type
    Recombinant
    Protein Characteristics
    Extracellular, AA 210-424
    Origin
    • 6
    • 4
    • 2
    Rat
    Source
    • 5
    • 3
    • 2
    • 2
    Yeast
    Purification tag / Conjugate
    This NADPH Oxidase 4 protein is labelled with His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    GGLLKYQTNL DTHPPGCISL NRTPSQNMSI ADYVSEHFHG SLPGGFSKLE DHYQKTLVKI CLEEPKFQAH FPQTWIWISG PLCLYCAERL YRCIRSNKPV TIISVINHPS DVMELRMIKE NFKARPGQYI ILHCPSVSAL ENHPFTLTMC PTETKATFGV HFKVVGDWTE RFRDLLLPPS SQDSEILPFI QSRNYPKLYI DGPFGSPFEE SLNYE
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product NOX4 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    NADPH Oxidase 4 (NOX4)
    Alternative Name
    NOX4 (NOX4 Products)
    Synonyms
    KOX Protein, KOX-1 Protein, RENOX Protein, AI648021 Protein, nox4 Protein, NOX4 Protein, NADPH oxidase 4 Protein, NOX4 Protein, Nox4 Protein, nox4 Protein, PTRG_09562 Protein
    Background
    Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
    Molecular Weight
    40.6 kDa
    UniProt
    Q924V1
    Pathways
    Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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