SIRT5 Protein (AA 34-310) (His tag)
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- Target See all SIRT5 Proteins
- SIRT5 (Sirtuin 5 (SIRT5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 34-310
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SIRT5 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSARPSSSM ADFRKFFAKA KHIVIISGAG VSAESGVPTF RGAGGYWRKW QAQDLATPLA FAHNPSRVWE FYHYRREVMG SKEPNAGHRA IAECETRLGK QGRRVVVITQ NIDELHRKAG TKNLLEIHGS LFKTRCTSCG VVAENYKSPI CPALSGKGAP EPGTQDASIP VEKLPRCEEA GCGGLLRPHV VWFGENLDPA ILEEVDRELA HCDLCLVVGT SSVVYPAAMF APQVAARGVP VAEFNTETTP ATNRFRFHFQ GPCGTTLPEA LACHENETVS
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SIRT5 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 30 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- SIRT5 (Sirtuin 5 (SIRT5))
- Alternative Name
- SIRT5 (SIRT5 Products)
- Synonyms
- SIR2L5 Protein, 0610012J09Rik Protein, 1500032M05Rik Protein, AV001953 Protein, zgc:92288 Protein, sirt5-a Protein, SIRT5 Protein, sir2l5 Protein, sirtuin 5 Protein, sirtuin 5 L homeolog Protein, SIRT5 Protein, Sirt5 Protein, sirt5 Protein, sirt5.L Protein, CC1G_00083 Protein
- Background
- SIRT5 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants Recombinant human SIRT5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 32.5kDa (300aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_036373
- UniProt
- Q9NXA8
- Pathways
- SARS-CoV-2 Protein Interactome
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