PRKAR2A Protein (AA 1-404) (His tag)

Catalog No. ABIN5854185

Product Details

Target: PRKAR2A (Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))

Protein Type: Recombinant

Protein Characteristics: AA 1-404

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PRKAR2A protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSHIQIP PGLTELLQGY TVEVLRQQPP DLVEFAVEYF TRLREARAPA SVLPAATPRQ SLGHPPPEPG PDRVADAKGD SESEEDEDLE VPVPSRFNRR VSVCAETYNP DEEEEDTDPR VIHPKTDEQR CRLQEACKDI LLFKNLDQEQ LSQVLDAMFE RIVKADEHVI DQGDDGDNFY VIERGTYDIL VTKDNQTRSV GQYDNRGSFG ELALMYNTPR AATIVATSEG SLWGLDRVTF RRIIVKNNAK KRKMFESFIE SVPLLKSLEV SERMKIVDVI GEKIYKDGER IITQGEKADS FYIIESGEVS ILIRSRTKSN KDGGNQEVEI ARCHKGQYFG ELALVTNKPR AASAYAVGDV KCLVMDVQAF ERLLGPCMDI MKRNISHYEE QLVKMFGSSV DLGNLGQ

Purity: > 85 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid, In Phosphate buffered saline (  pH 7.4) containing 10 % glycerol, 1  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: PRKAR2A (Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))

Alternative Name: PRKAR2A (PRKAR2A Products)

Synonyms: PKR2 Protein, PRKAR2 Protein, prkar2a Protein, zgc:85886 Protein, PRKAR2A Protein, 1110061A24Rik Protein, AI317181 Protein, AI836829 Protein, RII(alpha) Protein, protein kinase cAMP-dependent type II regulatory subunit alpha Protein, protein kinase, cAMP-dependent, regulatory, type II, alpha, B Protein, protein kinase, cAMP-dependent, regulatory, type II, alpha Protein, protein kinase, cAMP dependent regulatory, type II alpha Protein, protein kinase cAMP-dependent type 2 regulatory subunit alpha Protein, PRKAR2A Protein, prkar2ab Protein, Prkar2a Protein

Background: PRKAR2A also known as cAMP-dependent protein kinase type II-alpha regulatory subunit. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. Recombinant human PRKAR2A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 48.6kDa (434aa) confirmed by MALDI-TOF

NCBI Accession: NP_004148

UniProt: P13861

Pathways: Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection