IL2RG Protein (AA 23-262) (His tag)

Catalog No. ABIN5854210

Product Details

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Protein Type: Recombinant

Protein Characteristics: AA 23-262

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This IL2RG protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: LNTTILTPNG NEDTTADFFL TTMPTDSLSV STLPLPEVQC FVFNVEYMNC TWNSSSEPQP TNLTLHYWYK NSDNDKVQKC SHYLFSEEIT SGCQLQKKEI HLYQTFVVQL QDPREPRRQA TQMLKLQNLV IPWAPENLTL HKLSESQLEL NWNNRFLNHC LEHLVQYRTD WDHSWTEQSV DYRHKFSLPS VDGQKRYTFR VRSRFNPLCG SAQHWSEWSH PIHWGSNTSK ENPFLFALEA HHHHHH

Purity: > 90 % by SDS - PAGE.

Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate buffer saline (  pH 7.4)

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Alternative Name: IL2RG (IL2RG Products)

Synonyms: Ab2-183 Protein, Cd132 Protein, CD132 Protein, CIDX Protein, IL-2RG Protein, IMD4 Protein, P64 Protein, SCIDX Protein, SCIDX1 Protein, [g]c Protein, gamma(c) Protein, gc Protein, interleukin 2 receptor subunit gamma Protein, interleukin 2 receptor subunit gamma L homeolog Protein, interleukin 2 receptor, gamma chain Protein, IL2RG Protein, il2rg.L Protein, Il2rg Protein

Background: IL2RG, also known as Interleukin-2 receptor common subunit gamma, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors. This protein is located on the surface of immature blood-forming cells in bone marrow. One end of the protein resides outside of the cell where it binds to cytokines and the other end of the protein resides in the interior of the cell where it transmits signals to the cell's nucleus. The common gamma chain partners with other proteins to direct blood-forming cells to form lymphocytes. It also directs the growth and maturation of lymphocyte subtypes. These cells kill viruses, make antibodies, and help regulate the entire immune system. Recombinant human IL2RG, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 29.0KDa (246aa) 40-57kDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_000197

UniProt: P31785

Pathways: JAK-STAT Signaling, Growth Factor Binding