PPP2R1A Protein (AA 1-589) (His tag)

Catalog No. ABIN5854332

Product Details

Target: PPP2R1A (Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))

Protein Type: Recombinant

Protein Characteristics: AA 1-589

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PPP2R1A protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAAADGD DSLYPIAVLI DELRNEDVQL RLNSIKKLST IALALGVERT RSELLPFLTD TIYDEDEVLL ALAEQLGTFT TLVGGPEYVH CLLPPLESLA TVEETVVRDK AVESLRAISH EHSPSDLEAH FVPLVKRLAG GDWFTSRTSA CGLFSVCYPR VSSAVKAELR QYFRNLCSDD TPMVRRAAAS KLGEFAKVLE LDNVKSEIIP MFSNLASDEQ DSVRLLAVEA CVNIAQLLPQ EDLEALVMPT LRQAAEDKSW RVRYMVADKF TELQKAVGPE ITKTDLVPAF QNLMKDCEAE VRAAASHKVK EFCENLSADC RENVIMSQIL PCIKELVSDA NQHVKSALAS VIMGLSPILG KDNTIEHLLP LFLAQLKDEC PEVRLNIISN LDCVNEVIGI RQLSQSLLPA IVELAEDAKW RVRLAIIEYM PLLAGQLGVE FFDEKLNSLC MAWLVDHVYA IREAATSNLK KLVEKFGKEW AHATIIPKVL AMSGDPNYLH RMTTLFCINV LSEVCGQDIT TKHMLPTVLR MAGDPVANVR FNVAKSLQKI GPILDNSTLQ SEVKPILEKL TQDQDVDVKY FAQEALTVLS LA

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: PPP2R1A (Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))

Alternative Name: PPP2R1A (PPP2R1A Products)

Synonyms: PP2A-Aalpha Protein, PP2AAALPHA Protein, PR65A Protein, PR65 Protein, pp2a-aalpha Protein, pp2aaalpha Protein, ppp2r1a Protein, pr65a Protein, wu:fa02h04 Protein, zgc:56296 Protein, 6330556D22Rik Protein, PP2A Protein, ppp2r1a-a Protein, ppp2r1a-b Protein, protein phosphatase 2 scaffold subunit Aalpha Protein, protein phosphatase 2 scaffold subunit A alpha Protein, protein phosphatase 2 regulatory subunit A, alpha L homeolog Protein, protein phosphatase 2 regulatory subunit A, alpha Protein, protein phosphatase 2, regulatory subunit A, beta a Protein, serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Protein, protein phosphatase 2, regulatory subunit A, alpha isoform Protein, protein phosphatase 2, regulatory subunit A, alpha Protein, protein phosphatase 2 regulatory subunit A, alpha S homeolog Protein, PPP2R1A Protein, Ppp2r1a Protein, ppp2r1a.L Protein, ppp2r1a Protein, ppp2r1ba Protein, LOC583227 Protein, ppp2r1a.S Protein

Background: PPP2R1A also known as Serine/Threonine-Protein Phosphatase 2A 65 kDa regulatory subunit A alpha isoform, is a member of the PPP family of phosphatases, regulates a variety of essential cellular processes. PPP2R1A phosphorylation is an in vivo mechanism for regulation of the PP2A signaling complex and increased PP2A activity in heart failure. Recombinant human PPP2R1A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 67.7kDa (612aa)

NCBI Accession: NP_055040

UniProt: P30153

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, M Phase, Hepatitis C, Toll-Like Receptors Cascades