CLEC7A Protein (AA 71-244) (His tag)
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- Target See all CLEC7A Proteins
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 71-244
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Origin
- Mouse
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CLEC7A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPRHNSGRN PEEKDNFLSR NKENHKPTES SLDEKVAPSK ASQTTGGFSQ SCLPNWIMHG KSCYLFSFSG NSWYGSKRHC SQLGAHLLKI DNSKEFEFIE SQTSSHRINA FWIGLSRNQS EGPWFWEDGS AFFPNSFQVR NTVPQESLLH NCVWIHGSEV YNQICNTSSY SICEKELHHH HHH
- Purity
- > 95 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product CLEC7A Protein
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C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 71-244) protein (Fc Tag)
CLEC7A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 66-201) protein (Fc Tag)CLEC7A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 1-77) protein (GST tag)CLEC7A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
C-Type Lectin Domain Family 7, Member A (CLEC7A) protein (His tag)CLEC7A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
- Alternative Name
- C-type lectin domain family 7 member A 1 (CLEC7A Products)
- Synonyms
- CLEC7A Protein, BGR Protein, Clecsf12 Protein, beta-GR Protein, CANDF4 Protein, CLECSF12 Protein, DECTIN1 Protein, Clec7b Protein, RGD1565140 Protein, C-type lectin domain containing 7A Protein, C-type lectin domain family 7, member a Protein, CLEC7A Protein, Clec7a Protein
- Background
- CLEC7A, also known as C-type lectin domain family 7 member A 1, that functions as in the innate immune response to fungal pathogens. It is expressed on monocytes, macrophages, and neutrophils, and on some populations of dendritic cells and T cells. It is upregulated on macrophages by GM-CSF, IL-4, or IL-13 and downregulated by dexamethasone, IL-10, or LPS. Recombinant mouse CLEC7A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 21.0kDa (183aa) 18-28KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_064392
- Pathways
- Activation of Innate immune Response
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