GZMB Protein (AA 19-247) (His tag)
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- Target See all GZMB Proteins
- GZMB (Granzyme B (GZMB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-247
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GZMB protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MSLMKNERAI IMSMWEKMAA QAEPIGTETL ERLFCSYPQT KTYFPHFDLH HGSQQLRAHG FKIMTAVGDA VKSIDNLSSA LTKLSELHAY ILRVDPVNFK LLSHCLLVTM AARFPADFTP EVHEAWDKFM SILSSILTEK YR
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product GZMB Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Bioactivity Validated
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM MES( pH 6.0) containing 0.1M NaCl, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- GZMB (Granzyme B (GZMB))
- Alternative Name
- GZMB (GZMB Products)
- Synonyms
- CCPI Protein, CGL-1 Protein, CGL1 Protein, CSP-B Protein, CSPB Protein, CTLA1 Protein, CTSGL1 Protein, HLP Protein, SECT Protein, granzyme B Protein, GZMB Protein
- Background
- Hba-x, also known as Hemoglobin subunit zeta (Hbz), is belongs to the globin family. Zeta-globin is alpha-like hemoglobin. The Hba-x polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. Hba-x gene includes five functional genes and two pseudogenes. The order of genes is: 5' -zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'. Recombinant mouse Hba-x fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 18.3 kDa (162aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_034535
- UniProt
- P06467
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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