ANGPTL7 Protein (AA 27-346) (Fc Tag,AVI tag,Biotin)

Catalog No. ABIN5954950

Product Details

Target: ANGPTL7 (Angiopoietin-Like 7 (ANGPTL7))

Protein Type: Recombinant

Biological Activity: Active

Protein Characteristics: AA 27-346

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ANGPTL7 protein is labelled with Fc Tag,AVI tag,Biotin.

Sequence: AA 27-346

Specificity: Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

Purity: >90 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Comment:

Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Tris with Glycine, Arginine and NaCl,  pH 7.5

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Target Details

Target: ANGPTL7 (Angiopoietin-Like 7 (ANGPTL7))

Alternative Name: ANGPTL7 (ANGPTL7 Products)

Synonyms: AngX Protein, CDT6 Protein, RP4-647M16.2 Protein, dJ647M16.1 Protein, MGC84421 Protein, zgc:101687 Protein, angiopoietin like 7 Protein, angiopoietin-like 7 Protein, angiopoietin like 7 S homeolog Protein, ANGPTL7 Protein, Angptl7 Protein, angptl7.S Protein, angptl7 Protein

Background: Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.

Molecular Weight: 65.8 kDa

NCBI Accession: NP_066969