ANGPTL7 Protein (His tag)
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- Target See all ANGPTL7 Proteins
- ANGPTL7 (Angiopoietin-Like 7 (ANGPTL7))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ANGPTL7 protein is labelled with His tag.
- Purpose
- Active Recombinant Human Angiopoietin-like 7/ANGPTL7 Protein
- Sequence
- QKLSKHKTPA QPQLKAANCC EEVKELKAQV ANLSSLLSEL NKKQERDWVS VVMQVMELES NSKRMESRLT DAESKYSEMN NQIDIMQLQA AQTVTQTSAD AIYDCSSLYQ KNYRISGVYK LPPDDFLGSP ELEVFCDMET SGGGWTIIQR RKSGLVSFYR DWKQYKQGFG SIRGDFWLGN EHIHRLSRQP TRLRVEMEDW EGNLRYAEYS HFVLGNELNS YRLFLGNYTG NVGNDALQYH NNTAFSTKDK DNDNCLDKCA QLRKGGYWYN CCTDSNLNGV YYRLGEHNKH LDGITWYGWH GSTYSLKRVE MKIRPEDFKP
- Specificity
- Gln27-Pro346
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human ANGPTL7 at 5 μg/mL (100 μL/well) can bind Recombinant Human LILRB4 with a linear range of 0.5-3.5 μg/mL.
- Top Product
- Discover our top product ANGPTL7 Protein
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Angiopoietin-Like 7 (ANGPTL7) (AA 1-346) protein (GST tag)
ANGPTL7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Angiopoietin-Like 7 (ANGPTL7) (AA 27-346) (Active) protein (His tag)ANGPTL7 Origin: Human Host: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
Angiopoietin-Like 7 (ANGPTL7) (AA 27-346) (Active) protein (Fc Tag,AVI tag,Biotin)ANGPTL7 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Angiopoietin-Like 7 (ANGPTL7) (AA 27-346) (Active) protein (Fc Tag)ANGPTL7 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- ANGPTL7 (Angiopoietin-Like 7 (ANGPTL7))
- Alternative Name
- Angiopoietin-like 7/ANGPTL7 (ANGPTL7 Products)
- Synonyms
- AngX Protein, CDT6 Protein, RP4-647M16.2 Protein, dJ647M16.1 Protein, MGC84421 Protein, zgc:101687 Protein, angiopoietin like 7 Protein, angiopoietin-like 7 Protein, angiopoietin like 7 S homeolog Protein, ANGPTL7 Protein, Angptl7 Protein, angptl7.S Protein, angptl7 Protein
- Background
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Description: Angiopoietin-like 7 (ANGPTL7), also known as Corneal-Derived Transcript 6 (CDT6), is a secreted glycoprotein that is structurally related to the angiopoietins. ANGPTL7 is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Its production is up regulated in trabecular meshwork cells by glucocorticoids and TGF-beta and in cartilage by TNF-alpha. Overexpression of ANGPTL7 in trabecular meshwork cells inhibits the production of collagen and proteoglycans . When overexpressed in tumor cells it promotes collagen and proteoglycan deposition but inhibits tumor xenograft progression and tumor angiogenesis.
Name: ANGPTL7,AngX,CDT6,dJ647M16.1
- Gene ID
- 10218
- UniProt
- O43827
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