ANGPTL7 Protein (AA 27-346) (His-Avi Tag)

Catalog No. ABIN7454075

Product Details

Target: ANGPTL7 (Angiopoietin-Like 7 (ANGPTL7))

Protein Type: Recombinant

Protein Characteristics: AA 27-346

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ANGPTL7 protein is labelled with His-Avi Tag.

Purpose: Human ANGPTL7/CDT6 Protein

Sequence: GIn27-Pro346

Characteristics: Recombinant Human ANGPTL7/CDT6 Protein is expressed from HEK293 with His and Avi tag at the C-Terminus.It contains GIn27-Pro346.

Purity: > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: ANGPTL7 (Angiopoietin-Like 7 (ANGPTL7))

Alternative Name: ANGPTL7 (ANGPTL7 Products)

Synonyms: AngX Protein, CDT6 Protein, RP4-647M16.2 Protein, dJ647M16.1 Protein, MGC84421 Protein, zgc:101687 Protein, angiopoietin like 7 Protein, angiopoietin-like 7 Protein, angiopoietin like 7 S homeolog Protein, ANGPTL7 Protein, Angptl7 Protein, angptl7.S Protein, angptl7 Protein

Background: Angiopoietin-like 7 (ANGPTL7), also known as Corneal-Derived Transcript 6 (CDT6), is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL7 is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Its production is up-regulated in trabecular meshwork cells by glucocorticoids and TGF-beta and in cartilage by TNF-alpha.

Molecular Weight: 40.2 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.

UniProt: O43827