SIGLEC10 Protein (AA 17-546) (Fc Tag)
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- Target See all SIGLEC10 Proteins
- SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 17-546
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SIGLEC10 protein is labelled with Fc Tag.
- Sequence
- AA 17-546
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product SIGLEC10 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
- Alternative Name
- Siglec-10 (SIGLEC10 Products)
- Synonyms
- PRO940 Protein, SIGLEC-10 Protein, SLG2 Protein, Siglecg Protein, SIGLEC10 Protein, slg2 Protein, pro940 Protein, siglec-10 Protein, sialic acid binding Ig like lectin 10 Protein, sialic acid binding Ig-like lectin 10 Protein, sialic acid-binding Ig-like lectin 10 Protein, SIGLEC10 Protein, Siglec10 Protein, LOC484343 Protein, LOC100066644 Protein, siglec10 Protein, LOC100513863 Protein, LOC100340374 Protein
- Background
- The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
- Molecular Weight
- 85.6 kDa
- NCBI Accession
- NP_149121
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