CD22 Protein (AA 20-686) (His tag)
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- Target See all CD22 Proteins
- CD22 (CD22 Molecule (CD22))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-686
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Origin
- Rhesus Monkey
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD22 protein is labelled with His tag.
- Sequence
- AA 20-686
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CD22 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- CD22 (CD22 Molecule (CD22))
- Alternative Name
- Siglec-2 (CD22 Products)
- Synonyms
- A530093D23 Protein, Lyb-8 Protein, Lyb8 Protein, SIGLEC-2 Protein, SIGLEC2 Protein, siglec-2 Protein, CD22 antigen Protein, CD22 molecule Protein, Cd22 Protein, CD22 Protein
- Background
- B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
- Molecular Weight
- 76.9 kDa
- NCBI Accession
- XP_014979161
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