IL7R Protein (AA 21-236) (Fc Tag)
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- Target See all IL7R Proteins
- IL7R (Interleukin 7 Receptor (IL7R))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 21-236
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL7R protein is labelled with Fc Tag.
- Sequence
- AA 21-236
- Characteristics
- This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 52 kDa. The protein migrates as 65-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL7R Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- IL7R (Interleukin 7 Receptor (IL7R))
- Alternative Name
- IL-7 R alpha (IL7R Products)
- Synonyms
- IL7R Protein, CD127 Protein, IL-7Ralpha Protein, CDW127 Protein, IL-7R-alpha Protein, IL7RA Protein, ILRA Protein, IL-7RA Protein, interleukin 7 receptor Protein, IL7R Protein, Il7r Protein
- Background
- Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.
- Molecular Weight
- 52.0 kDa
- Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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