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IL7R Protein (AA 21-236) (Fc Tag)

IL7R Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Catalog No. ABIN6253694
  • Target See all IL7R Proteins
    IL7R (Interleukin 7 Receptor (IL7R))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 21-236
    Origin
    • 19
    • 8
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 11
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL7R protein is labelled with Fc Tag.
    Sequence
    AA 21-236
    Characteristics
    This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 52 kDa. The protein migrates as 65-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >90 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL7R Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
  • Target
    IL7R (Interleukin 7 Receptor (IL7R))
    Alternative Name
    IL-7 R alpha (IL7R Products)
    Synonyms
    IL7R Protein, CD127 Protein, IL-7Ralpha Protein, CDW127 Protein, IL-7R-alpha Protein, IL7RA Protein, ILRA Protein, IL-7RA Protein, interleukin 7 receptor Protein, IL7R Protein, Il7r Protein
    Background
    Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.
    Molecular Weight
    52.0 kDa
    Pathways
    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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